Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 2/20 | 0.42 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.41 |
| ▸ | HRH1 | P35367 | 3/20 | 0.41 |
| ▸ | DRD2 | P14416 | 3/20 | 0.41 |
| ▸ | HTR6 | P50406 | 3/20 | 0.41 |
| ▸ | HTR1A | P08908 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | HTR7 | P34969 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6970428 | 0.93 | CYP2D6 (0.43) | AVPR1AAVPR2SLC6A4HRH1DRD2 | |
| SCHEMBL6970673 | 0.89 | AVPR2 (0.48) | AVPR1AAVPR2SLC6A4HRH1DRD2 | |
| SCHEMBL6972375 | 0.84 | KDM4E (0.43) | SLC6A4HRH1DRD2HTR6HTR1A | |
| SCHEMBL6969600 | 0.82 | AVPR2 (0.46) | AVPR1AAVPR2SLC6A4HRH1DRD2 | |
| SCHEMBL6967996 | 0.79 | AVPR2 (0.47) | AVPR1AAVPR2SLC6A4HRH1DRD2 | |
| SCHEMBL6969043 | 0.78 | DRD3 (0.47) | AVPR2SLC6A4HRH1DRD2HTR6 | |
| SCHEMBL6960675 | 0.77 | AVPR2 (0.53) | AVPR1AAVPR2 | |
| SCHEMBL6959586 | 0.76 | HDAC1 (0.49) | AVPR1AAVPR2KCNN4KCNA3HDAC1 | |
| SCHEMBL6960423 | 0.75 | AVPR2 (0.58) | AVPR1AAVPR2 | |
| SCHEMBL27352381 | 0.74 | AVPR2 (0.40) | AVPR1AAVPR2PHLPP2P2RX4CACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0620216-B1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO (JP) | 2003-01-08 | — | — | EP | disclosed |
| US-5521170-A | VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-28 | — | — | US | disclosed |
| EP-0620216-A1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-19 | — | — | EP | disclosed |