Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | HTR1A | P08908 | 4/20 | 0.43 |
| ▸ | DRD2 | P14416 | 4/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.43 |
| ▸ | PRNP | P04156 | 3/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.43 |
| ▸ | DRD1 | P21728 | 3/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.43 |
| ▸ | DRD3 | P35462 | 3/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6959648 | 0.93 | AVPR1A (0.42) | LMNAHTR1ADRD2SLC6A4CHRM2 | |
| SCHEMBL6969600 | 0.89 | AVPR2 (0.46) | CYP2D6LMNAHTR1ADRD2SLC6A4 | |
| SCHEMBL6969043 | 0.85 | DRD3 (0.47) | CYP2D6LMNAHTR1ADRD2SLC6A4 | |
| SCHEMBL6970673 | 0.82 | AVPR2 (0.48) | LMNAHTR1ADRD2SLC6A4CHRM2 | |
| SCHEMBL6967996 | 0.81 | AVPR2 (0.47) | HTR1ADRD2SLC6A4CHRM2CHRM1 | |
| SCHEMBL6972375 | 0.78 | KDM4E (0.43) | LMNAHTR1ADRD2SLC6A4CHRM2 | |
| SCHEMBL6959966 | 0.78 | AVPR2 (0.58) | AVPR2AVPR1A | |
| SCHEMBL6972489 | 0.76 | AVPR2 (0.63) | AVPR2AVPR1A | |
| SCHEMBL27362645 | 0.75 | AVPR2 (0.40) | CYP2D6LMNAHTR1ADRD2SLC6A4 | |
| SCHEMBL6958687 | 0.75 | DRD3 (0.46) | CYP2D6LMNAHTR1ADRD2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0620216-B1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO (JP) | 2003-01-08 | — | — | EP | disclosed |
| US-5521170-A | VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-28 | — | — | US | disclosed |
| EP-0620216-A1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-19 | — | — | EP | disclosed |