Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 5/20 | 0.48 |
| ▸ | AVPR1A | P37288 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | HRH1 | P35367 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | HTR6 | P50406 | 2/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6969600 | 0.94 | AVPR2 (0.46) | AVPR2AVPR1ARAB9ASMN1; SMN2NPC1 | |
| SCHEMBL6959648 | 0.89 | AVPR1A (0.42) | AVPR2AVPR1AHPGDALDH1A1LMNA | |
| SCHEMBL6955542 | 0.85 | ALDH1A1 (0.43) | RAB9ANPC1HPGDKMT2AALDH1A1 | |
| SCHEMBL6970428 | 0.82 | CYP2D6 (0.43) | AVPR2AVPR1ASMN1; SMN2HPGDKMT2A | |
| SCHEMBL6972107 | 0.81 | NOTUM (0.46) | AVPR2AVPR1ARAB9ASMN1; SMN2NPC1 | |
| SCHEMBL6964588 | 0.81 | AVPR2 (0.46) | AVPR2AVPR1ARAB9ASMN1; SMN2NPC1 | |
| SCHEMBL6967260 | 0.80 | AVPR2 (0.48) | AVPR2AVPR1ARAB9ASMN1; SMN2NPC1 | |
| SCHEMBL6958687 | 0.79 | DRD3 (0.46) | AVPR2HPGDKMT2AALDH1A1LMNA | |
| SCHEMBL6957126 | 0.79 | NOTUM (0.44) | AVPR2AVPR1ARAB9ASMN1; SMN2NPC1 | |
| SCHEMBL6960127 | 0.78 | NPSR1 (0.49) | AVPR2AVPR1ARAB9ASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0620216-B1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO (JP) | 2003-01-08 | — | — | EP | disclosed |
| US-5521170-A | VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-28 | — | — | US | disclosed |
| EP-0620216-A1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-19 | — | — | EP | disclosed |