Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | HTR1A | P08908 | 1/20 | 0.59 |
| ▸ | MAOA | P21397 | 1/20 | 0.59 |
| ▸ | MAOB | P27338 | 1/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL45567 | 0.88 | CYP2C9 (0.57) | POLBALDH1A1TSHRCYP2C9CYP2C19 | |
| SCHEMBL28602004 | 0.87 | POLB (0.60) | POLBCYP2C9CYP2C19MAPK1KDM4E | |
| SCHEMBL13164059 | 0.86 | MEN1 (0.66) | POLBALDH1A1CD274HPGDMAPK1 | |
| SCHEMBL280010 | 0.84 | P2RX7 (0.59) | POLBALDH1A1TSHRCD274HTR1A | |
| SCHEMBL12316416 | 0.83 | MEN1 (0.50) | POLBALDH1A1TSHRKCNH2 | |
| SCHEMBL12316415 | 0.83 | POLB (0.47) | POLBALDH1A1TSHRCYP2C9CYP2C19 | |
| SCHEMBL279958 | 0.81 | CYP2C19 (0.72) | POLBALDH1A1CYP2C9CYP2C19CD274 | |
| SCHEMBL8099123 | 0.81 | MAPK1 (0.54) | POLBALDH1A1TSHRCYP2C9CYP2C19 | |
| SCHEMBL280240 | 0.80 | MEN1 (0.76) | POLBALDH1A1TSHRCYP2C19CD274 | |
| SCHEMBL25040938 | 0.80 | KDM4E (0.69) | POLBALDH1A1CYP2C9CYP2C19KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024026483-A2 | CDK2 INHIBITORS AND METHODS OF USING THE SAME | CEDILLA THERAPEUTICS, INC. (US) | 2024-02-01 | — | — | WO | disclosed |