Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | BCL3 | P20749 | 2/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28612189 | 0.91 | TSHR (0.58) | POLBKDM4EBCL3 | |
| SCHEMBL13164059 | 0.90 | MEN1 (0.66) | POLBMEN1KMT2ABCL3MAPK1 | |
| SCHEMBL280010 | 0.88 | P2RX7 (0.59) | POLBMEN1KMT2ABCL3 | |
| SCHEMBL28598516 | 0.87 | NPSR1 (0.56) | POLBMEN1KMT2ACYP2C9 | |
| SCHEMBL27362945 | 0.87 | POLB (0.66) | POLBKDM4EMAPK1CYP2C9CYP2C19 | |
| SCHEMBL28612306 | 0.85 | KDM4E (0.53) | KDM4EMEN1KMT2A | |
| SCHEMBL45567 | 0.83 | CYP2C9 (0.57) | POLBMEN1KMT2ABCL3CYP2C9 | |
| SCHEMBL29849750 | 0.82 | BCL3 (0.76) | POLBKDM4EMEN1KMT2ABCL3 | |
| SCHEMBL16431474 | 0.82 | BCL3 (0.76) | POLBKDM4EMEN1KMT2ABCL3 | |
| SCHEMBL2362567 | 0.82 | POLB (0.66) | POLBKDM4EBCL3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113195497-A | Novel imidazopyrazine derivatives | 豪夫迈·罗氏有限公司 | 2021-07-30 | — | — | CN | claimed |
| CN-113195497-A | Novel imidazopyrazine derivatives | 豪夫迈·罗氏有限公司 | 2021-07-30 | — | — | CN | disclosed |