Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.66 |
| ▸ | RAB9A | P51151 | 9/20 | 0.66 |
| ▸ | NPC1 | O15118 | 7/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.57 |
| ▸ | LMNA | P02545 | 5/20 | 0.57 |
| ▸ | HTT | P42858 | 4/20 | 0.57 |
| ▸ | TSHR | P16473 | 4/20 | 0.57 |
| ▸ | USP2 | O75604 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | TP53 | P04637 | 6/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 5/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | CASP1 | P29466 | 1/20 | 0.52 |
| ▸ | CASP7 | P55210 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1033294 | 0.86 | TP53 (0.69) | MAPTRAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL27362955 | 0.84 | MAPT (0.56) | MAPTRAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL27361298 | 0.80 | RAB9A (0.57) | MAPTRAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL27362875 | 0.79 | RAB9A (0.56) | MAPTRAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL1034482 | 0.77 | MAPT (0.76) | MAPTRAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL1035549 | 0.73 | TP53 (0.76) | MAPTRAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL1035519 | 0.73 | MAPT (0.69) | MAPTRAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL1032957 | 0.73 | MAPT (0.58) | MAPTRAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL1034522 | 0.72 | MAPT (0.59) | MAPTRAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL1034707 | 0.71 | LMNA (0.85) | MAPTRAB9ANPC1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023235753-A2 | ALDH2 INHIBITORS AND METHODS OF USE THEREOF | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2023-12-07 | — | — | WO | disclosed |