Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.56 |
| ▸ | HTT | P42858 | 6/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.56 |
| ▸ | TSHR | P16473 | 6/20 | 0.56 |
| ▸ | NPC1 | O15118 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | USP2 | O75604 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 14/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.52 |
| ▸ | HPGD | P15428 | 5/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.52 |
| ▸ | TP53 | P04637 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27361298 | 0.81 | RAB9A (0.57) | RAB9AHTTSMN1; SMN2TSHRNPC1 | |
| SCHEMBL1033294 | 0.79 | TP53 (0.69) | RAB9ASMN1; SMN2TSHRNPC1LMNA | |
| SCHEMBL27362950 | 0.79 | MAPT (0.66) | RAB9AHTTSMN1; SMN2TSHRNPC1 | |
| SCHEMBL27362944 | 0.77 | SMN1; SMN2 (0.41) | RAB9AHTTSMN1; SMN2TSHRNPC1 | |
| SCHEMBL1034707 | 0.70 | LMNA (0.85) | RAB9AHTTSMN1; SMN2TSHRNPC1 | |
| SCHEMBL27362964 | 0.70 | MAPT (0.39) | RAB9AHTTSMN1; SMN2TSHRNPC1 | |
| SCHEMBL1034482 | 0.69 | MAPT (0.76) | RAB9ASMN1; SMN2TSHRNPC1LMNA | |
| SCHEMBL16689211 | 0.68 | TSHR (0.75) | RAB9AHTTSMN1; SMN2TSHRNPC1 | |
| SCHEMBL27362958 | 0.68 | MAPT (0.56) | RAB9AHTTSMN1; SMN2TSHRNPC1 | |
| SCHEMBL10077922 | 0.67 | MAPT (1.00) | RAB9AHTTSMN1; SMN2TSHRNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023235753-A2 | ALDH2 INHIBITORS AND METHODS OF USE THEREOF | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2023-12-07 | — | — | WO | disclosed |