Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 5/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ACR | P10323 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27361295 | 0.84 | KMT2A (0.51) | HPGDTP53RXFP1MEN1KMT2A | |
| SCHEMBL29924707 | 0.84 | MAPT (0.53) | HPGDTP53MEN1KMT2AMAPT | |
| SCHEMBL27362964 | 0.82 | MAPT (0.39) | HPGDTP53RXFP1MEN1KMT2A | |
| SCHEMBL22117098 | 0.82 | SMN1; SMN2 (0.53) | HPGDTP53MEN1KMT2AMAPT | |
| SCHEMBL5017019 | 0.82 | SMN1; SMN2 (0.51) | HPGDTP53MEN1KMT2AMAPT | |
| SCHEMBL27362958 | 0.80 | MAPT (0.56) | HPGDRECQLTP53RXFP1MEN1 | |
| SCHEMBL27362937 | 0.80 | MAPT (0.59) | HPGDRECQLTP53RXFP1MEN1 | |
| SCHEMBL29925367 | 0.74 | SMN1; SMN2 (0.48) | HPGDTP53MEN1KMT2AMAPT | |
| SCHEMBL21760981 | 0.73 | ALDH1A1 (0.43) | HPGDMEN1KMT2AMAPTNPC1 | |
| SCHEMBL3059986 | 0.73 | MAPT (0.48) | HPGDTP53MAPTNPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023235753-A2 | ALDH2 INHIBITORS AND METHODS OF USE THEREOF | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2023-12-07 | — | — | WO | disclosed |