Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 12/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 8/20 | 0.51 |
| ▸ | NPC1 | O15118 | 6/20 | 0.51 |
| ▸ | HPGD | P15428 | 5/20 | 0.51 |
| ▸ | TSHR | P16473 | 4/20 | 0.51 |
| ▸ | TP53 | P04637 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27361298 | 0.86 | RAB9A (0.57) | MAPTRXFP1RAB9ANPC1HPGD | |
| SCHEMBL1032957 | 0.84 | MAPT (0.58) | MAPTRXFP1RAB9ANPC1HPGD | |
| SCHEMBL1031278 | 0.82 | LMNA (0.66) | MAPTRXFP1RAB9ANPC1HPGD | |
| SCHEMBL27362955 | 0.82 | MAPT (0.56) | MAPTRXFP1RAB9ANPC1HPGD | |
| SCHEMBL1035519 | 0.82 | MAPT (0.69) | MAPTRAB9ANPC1HPGDTSHR | |
| SCHEMBL27362937 | 0.81 | MAPT (0.59) | MAPTRXFP1NPC1HPGDTP53 | |
| SCHEMBL27362971 | 0.80 | HPGD (0.51) | MAPTRXFP1NPC1HPGDTP53 | |
| SCHEMBL1035429 | 0.80 | MAPT (0.65) | MAPTRXFP1RAB9ANPC1HPGD | |
| SCHEMBL1033727 | 0.74 | TRPM8 (0.58) | MAPTRAB9ANPC1HPGDTSHR | |
| SCHEMBL10339173 | 0.74 | ALDH1A1 (0.45) | MAPTRAB9ANPC1HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4532016-A2 | ALDH2 INHIBITORS AND METHODS OF USE THEREOF | University of Maryland, Baltimore (US) | 2025-04-09 | — | — | EP | disclosed |
| WO-2023235753-A2 | ALDH2 INHIBITORS AND METHODS OF USE THEREOF | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2023-12-07 | — | — | WO | disclosed |
| WO-2023235753-A2 | ALDH2 INHIBITORS AND METHODS OF USE THEREOF | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2023-12-07 | — | — | WO | disclosed |