Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.59 |
| ▸ | TP53 | P04637 | 5/20 | 0.59 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | FLT3 | P36888 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27362934 | 0.85 | MAPT (0.59) | MAPTTP53RXFP1HPGDPOLB | |
| SCHEMBL27362958 | 0.81 | MAPT (0.56) | MAPTTP53RXFP1HPGDRECQL | |
| SCHEMBL27362971 | 0.80 | HPGD (0.51) | MAPTTP53RXFP1HPGDRECQL | |
| SCHEMBL20538978 | 0.76 | CDC7 (0.50) | MAPTTP53HPGDPOLBPTGS2 | |
| SCHEMBL2624439 | 0.73 | IDO1 (0.41) | MAPTTP53RXFP1HPGDPTGS2 | |
| SCHEMBL2564662 | 0.72 | IDO1 (0.43) | MAPTTP53RXFP1PTGS2MEN1 | |
| SCHEMBL13470766 | 0.72 | ALDH1A1 (0.43) | MAPTTP53HPGDPOLBPTGS2 | |
| SCHEMBL11327747 | 0.71 | GAA (0.45) | MAPTHPGDPOLBMEN1KMT2A | |
| SCHEMBL27361298 | 0.70 | RAB9A (0.57) | MAPTTP53RXFP1HPGDPOLB | |
| SCHEMBL13470789 | 0.70 | ALDH1A1 (0.40) | MAPTTP53HPGDPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023235753-A2 | ALDH2 INHIBITORS AND METHODS OF USE THEREOF | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2023-12-07 | — | — | WO | disclosed |