Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 3/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 14/20 | 0.43 |
| ▸ | F10 | P00742 | 3/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27356121 | 0.91 | GRM2 (0.42) | ITGB3ITGA2BSIGMAR1F10PRSS1 | |
| SCHEMBL27373853 | 0.89 | SIGMAR1 (0.39) | ITGB3ITGA2BSIGMAR1F10PRSS1 | |
| SCHEMBL8948669 | 0.89 | SIGMAR1 (0.43) | ITGB3ITGA2BSIGMAR1F10GRM2 | |
| SCHEMBL27419425 | 0.86 | ITGB3 (0.44) | ITGB3ITGA2BSIGMAR1F10PRSS1 | |
| SCHEMBL8948665 | 0.84 | F10 (0.52) | ITGB3ITGA2BSIGMAR1F10PRSS1 | |
| SCHEMBL8948621 | 0.84 | F10 (0.52) | ITGB3ITGA2BSIGMAR1F10PRSS1 | |
| SCHEMBL8310900 | 0.84 | F10 (0.52) | ITGB3ITGA2BSIGMAR1F10PRSS1 | |
| SCHEMBL8315207 | 0.82 | SIGMAR1 (0.45) | ITGB3ITGA2BSIGMAR1F10PRSS1 | |
| SCHEMBL8316462 | 0.82 | SIGMAR1 (0.46) | ITGB3ITGA2BSIGMAR1F10GRM2 | |
| SCHEMBL8312579 | 0.82 | SIGMAR1 (0.46) | ITGB3ITGA2BSIGMAR1F10GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1052231-C | Adhesion receptor antagonists | MERCK PATENT GMBH (DE) | 2000-05-10 | — | — | CN | disclosed |