Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | CCR1 | P32246 | 1/20 | 0.36 |
| ▸ | SMYD3 | Q9H7B4 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | BDKRB1 | P46663 | 2/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.34 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.34 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27376431 | 0.81 | JUN (0.38) | SMYD3 | |
| SCHEMBL24031696 | 0.75 | EZH2 (0.42) | — | |
| SCHEMBL26832626 | 0.75 | SMN1; SMN2 (0.54) | KDM4EGAAPOLB | |
| SCHEMBL19132762 | 0.74 | SMYD3 (0.46) | CCR1SMYD3KDM4EGAARORC | |
| SCHEMBL24233212 | 0.73 | OGG1 (0.46) | POLB | |
| SCHEMBL185580 | 0.73 | SMYD3 (0.54) | HCAR2SMYD3RORC | |
| SCHEMBL25059051 | 0.72 | CHRNA7 (0.39) | KDM4EGAA | |
| SCHEMBL24031980 | 0.72 | NPC1 (0.50) | KDM4EPOLB | |
| SCHEMBL22047308 | 0.71 | CHRNA7 (0.38) | SMYD3KDM4EGAAPOLB | |
| SCHEMBL22197853 | 0.71 | SMN1; SMN2 (0.48) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024054956-A1 | HETEROBIFUNCTIONAL COMPOUNDS AND METHODS OF TREATING DISEASE | HALDA THERAPEUTICS OPCO, INC. (US) | 2024-03-14 | — | — | WO | disclosed |