Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 13/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 12/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 12/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.37 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27539768 | 0.93 | ACHE (0.40) | ACHEMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL9029844 | 0.78 | HDAC1 (0.48) | ACHE | |
| SCHEMBL27424435 | 0.76 | TNF (0.47) | ACHE | |
| SCHEMBL9754203 | 0.76 | HDAC1 (0.46) | ACHE | |
| SCHEMBL9206920 | 0.74 | RXRA (0.48) | MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL27447114 | 0.73 | HDAC1 (0.56) | ACHE | |
| SCHEMBL9207495 | 0.71 | HDAC1 (0.50) | ACHEKMT2AALDH1A1NR3C1 | |
| SCHEMBL17602223 | 0.71 | DRD1 (0.48) | ACHEOPRM1OPRK1OPRD1 | |
| SCHEMBL17067809 | 0.71 | ALDH1A1 (0.53) | ACHEMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL27363198 | 0.71 | HDAC1 (0.57) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1060286-A | Antiinflammatory hydroxamic acids and N-hydroxyurea | PFIZER (US) | 1992-04-15 | — | — | CN | disclosed |