SCHEMBL27363485

SCHEMBL27363485

Cc1cccc2c1COC(NCCc1ccc(I)cc1)=N2

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.32
NPY1R P25929 1/20 0.31
BCHE P06276 1/20 0.30
ACHE P22303 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27362385 0.89 TAAR1 (0.37) GAABCHEACHE
SCHEMBL27379949 0.88 TAAR1 (0.37) GAANPY1RBCHEACHE
SCHEMBL27363486 0.75 ELANE (0.32)
SCHEMBL27362428 0.71 PKM (0.35) GAA
SCHEMBL27377429 0.71 ELANE (0.35)
SCHEMBL27364669 0.70 NPC1 (0.34)
SCHEMBL30122568 0.67 KDM4E (0.34) GAAACHE
SCHEMBL27357170 0.66 HDAC6 (0.38)
SCHEMBL27362384 0.63
SCHEMBL27358349 0.63 ELANE (0.43)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1070480-C 2-amino-benzoxanones for the treatment of viral infections SEARLE & CO (US) 2001-09-05 CN disclosed