Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2853118 | 0.75 | KMT2A (0.44) | GAARAB9AMEN1KMT2ANPC1 | |
| SCHEMBL27363078 | 0.73 | RAB9A (0.55) | TSHRGAAMAPK1RAB9AHPGD | |
| SCHEMBL27346655 | 0.71 | RAB9A (0.44) | TSHRGAAMAPK1RAB9AHPGD | |
| SCHEMBL3962528 | 0.71 | RAB9A (0.56) | TSHRGAAMAPK1RAB9AHPGD | |
| SCHEMBL11081245 | 0.70 | L3MBTL1 (0.56) | ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL2871628 | 0.70 | L3MBTL1 (0.56) | ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL11641690 | 0.70 | ALDH1A1 (0.54) | TSHRGAAMAPK1RAB9AHPGD | |
| SCHEMBL10831170 | 0.70 | PTGS1 (0.60) | MAPK1MEN1KMT2AALOX5 | |
| SCHEMBL10831167 | 0.70 | PTGS1 (0.60) | MAPK1MEN1KMT2AALOX5 | |
| SCHEMBL27363079 | 0.69 | MAPT (0.52) | TSHRRAB9AMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1057839-A | The azepine benzoglyoxaline that is used for the treatment of asthma, sacroiliitis and relative disease | PFIZER (US) | 1992-01-15 | — | — | CN | disclosed |