Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CBX7 | O95931 | 1/20 | 0.40 |
| ▸ | CDYL2 | Q8N8U2 | 1/20 | 0.40 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.40 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18258621 | 0.86 | IDO1 (0.50) | HPGDMAPK1SMN1; SMN2IDO1USP2 | |
| SCHEMBL18258625 | 0.86 | IDO1 (0.50) | HPGDMAPK1SMN1; SMN2IDO1USP2 | |
| SCHEMBL11181874 | 0.83 | ALDH1A1 (0.52) | HPGDMAPK1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL2600306 | 0.80 | MAPK1 (0.52) | HPGDMAPK1SMN1; SMN2IDO1USP2 | |
| SCHEMBL29591678 | 0.80 | MAPK1 (0.52) | HPGDMAPK1SMN1; SMN2IDO1USP2 | |
| SCHEMBL20812687 | 0.77 | MAPK1 (0.49) | HPGDMAPK1SMN1; SMN2IDO1USP2 | |
| SCHEMBL11157197 | 0.73 | MAPK1 (0.45) | HPGDMAPK1SMN1; SMN2IDO1USP2 | |
| SCHEMBL27363652 | 0.73 | MAPK1 (0.49) | HPGDMAPK1SMN1; SMN2IDO1USP2 | |
| SCHEMBL27984706 | 0.73 | POLB (0.47) | HPGDMAPK1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL16984805 | 0.72 | CDYL2 (0.44) | HPGDSMN1; SMN2IDO1ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1756071-A1 | BENZOXAZOLONE DERIVATIVES, PROCESSES FOR PREPARING THEM AND THEIR USES | UCB, S.A. (BE) | 2007-02-28 | — | — | EP | disclosed |
| WO-2005118561-A1 | BENZOXAZOLONE DERIVATIVES, PROCESSES FOR PREPARING THEM AND THEIR USES | UCB, S.A. (BE) | 2005-12-15 | — | — | WO | disclosed |
| EP-1434765-A1 | SUBSTITUTED PIPERIDINES WITH SELECTIVE BINDING TO HISTAMINE H3-RECEPTOR | NOVO NORDISK A/S (DK) | 2004-07-07 | — | — | EP | disclosed |
| WO-2003024929-A1 | SUBSTITUTED PIPERIDINES WITH SELECTIVE BINDING TO HISTAMINE H3-RECEPTOR | NOVO NORDISK A/S (DK) | 2003-03-27 | — | — | WO | disclosed |