Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 7/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16698725 | 0.81 | PKM (0.53) | PKMALDH1A1GAAMAPTATM | |
| SCHEMBL931348 | 0.81 | SIGMAR1 (0.49) | GAAMAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL8384325 | 0.79 | GAA (0.44) | ALDH1A1GAALMNASMN1; SMN2MEN1 | |
| SCHEMBL25035706 | 0.79 | PKM (0.56) | PKMALDH1A1GAAMAPTATM | |
| SCHEMBL92331 | 0.79 | L3MBTL1 (0.56) | ALDH1A1GAAMAPTMEN1KMT2A | |
| SCHEMBL7986031 | 0.78 | SIGMAR1 (0.58) | ALDH1A1LTA4HSMN1; SMN2SIGMAR1 | |
| SCHEMBL7279696 | 0.78 | PKM (0.63) | PKMALDH1A1GAAMAPTATM | |
| Bromide SCHEMBL28426487 | 0.77 | L3MBTL1 (0.54) | ALDH1A1GAAMAPTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL4768580 | 0.77 | L3MBTL1 (0.54) | ALDH1A1GAAMAPTMEN1KMT2A | |
| SCHEMBL21384057 | 0.77 | PKM (0.62) | PKMALDH1A1GAAMAPTATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1067068-C | Heterocyclic subsitituted piperazinone derivatives as tachykinin receptor antagonists | HOECHST PHARMACEUTICAL CORP (US) | 2001-06-13 | — | — | CN | disclosed |