Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27391812 | 0.96 | PKM (0.59) | PKMCTDSP1MEN1KMT2ANPC1 | |
| SCHEMBL2465315 | 0.94 | PKM (0.62) | PKMCTDSP1MEN1KMT2ANPC1 | |
| SCHEMBL26629764 | 0.92 | PKM (0.55) | PKMCTDSP1MEN1KMT2ANPC1 | |
| SCHEMBL15179028 | 0.82 | PKM (0.43) | PKMCTDSP1MEN1KMT2ANPC1 | |
| SCHEMBL7428096 | 0.81 | MEN1 (0.55) | PKMCTDSP1MEN1KMT2AGAA | |
| SCHEMBL93039 | 0.80 | OPRD1 (0.48) | PKMCTDSP1SLC6A2SLC6A3 | |
| SCHEMBL21753666 | 0.80 | ESR1 (0.50) | PKMCTDSP1MEN1KMT2ANPC1 | |
| SCHEMBL22863375 | 0.80 | PKM (0.44) | PKMCTDSP1MEN1KMT2ALMNA | |
| SCHEMBL9346690 | 0.80 | PKM (0.44) | PKMCTDSP1MEN1KMT2AGAA | |
| SCHEMBL16191249 | 0.80 | PKM (0.68) | PKMCTDSP1MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1068816-A | indole derivatives | PFIZER (US) | 1993-02-10 | — | — | CN | disclosed |