Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | ACE2 | Q9BYF1 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.39 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.38 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MYC | P01106 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1355576 | 0.90 | ACE2 (0.45) | ACE2NPC1GAAGRIN2DGRIN2A | |
| SCHEMBL7015710 | 0.82 | ALDH1A1 (0.48) | NPC1GAAKMT2AAKR1C3AKR1C2 | |
| SCHEMBL1356439 | 0.81 | ACE2 (0.50) | ACE2NPC1GAAGRIN2DGRIN2A | |
| SCHEMBL27417362 | 0.79 | AKR1C3 (0.41) | ACE2GAAAKR1C3AKR1C2CREBBP | |
| SCHEMBL2538201 | 0.79 | EPHX2 (0.49) | ALOX15ACE2NPC1GAAGRIN2D | |
| SCHEMBL23346538 | 0.79 | ALDH1A1 (0.46) | ACE2NPC1GAAGRIN2DGRIN2A | |
| SCHEMBL17059386 | 0.79 | AKR1C3 (0.41) | ACE2GAAAKR1C3AKR1C2CREBBP | |
| SCHEMBL7772612 | 0.79 | KDM4E (0.52) | ACE2GAAGRIN2DGRIN2AGRIN2B | |
| SCHEMBL7468951 | 0.79 | APEX1 (0.43) | ACE2GAAKMT2AAKR1C3AKR1C2 | |
| Hydrochloric Acid SCHEMBL8641151 | 0.78 | TPH1 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1068308-C | Substituted benzoylguanide preparation and pharmaceutical application of same | HOECHST AG (DE) | 2001-07-11 | — | — | CN | disclosed |
| CN-1097737-A | Benzoyl guanidine, its method for making that replaces and contain their medicine and application | HOECHST AG (DE) | 1995-01-25 | — | — | CN | disclosed |