Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 5/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 5/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.40 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.40 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7015710 | 0.85 | ALDH1A1 (0.48) | POLBMEN1KMT2AAKR1C3AKR1C2 | |
| SCHEMBL27417362 | 0.82 | AKR1C3 (0.41) | POLBAKR1C3AKR1C2NR1H4AKR1B10 | |
| SCHEMBL17059386 | 0.82 | AKR1C3 (0.41) | POLBAKR1C3AKR1C2AKR1B10AKR1B1 | |
| SCHEMBL2427030 | 0.80 | SRC (0.57) | POLBMEN1KMT2ABCAT2SRC | |
| SCHEMBL27554809 | 0.80 | KDM4E (0.44) | POLBAKR1C3AKR1C2AKR1B10AKR1B1 | |
| SCHEMBL27363777 | 0.79 | ALOX15 (0.44) | KMT2AAKR1C3AKR1C2AKR1B10AKR1B1 | |
| SCHEMBL17059420 | 0.79 | HTR7 (0.50) | MEN1KMT2AAKR1C3AKR1C2NR1H4 | |
| SCHEMBL14235189 | 0.78 | NR1H4 (0.52) | MEN1KMT2ANR1H4SRCKDM4E | |
| SCHEMBL30019444 | 0.77 | KDM4E (0.59) | APEX1POLBMEN1KMT2AAKR1B1 | |
| SCHEMBL5813467 | 0.77 | KDM4E (0.59) | APEX1POLBMEN1KMT2AAKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1077701-A4 | ANTI-VIRAL COMPOUNDS | LILLY CO ELI (US) | 2002-03-20 | — | — | EP | disclosed |
| EP-1077701-A1 | ANTI-VIRAL COMPOUNDS | ELI LILLY AND COMPANY (US) | 2001-02-28 | — | — | EP | disclosed |
| WO-1999059587-A1 | ANTI-VIRAL COMPOUNDS | ELI LILLY AND COMPANY (US) | 1999-11-25 | — | — | WO | disclosed |