Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.70 |
| ▸ | POLB | P06746 | 1/20 | 0.70 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.70 |
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | TAS2R8 | Q9NYW2 | 2/20 | 0.46 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13692389 | 0.86 | L3MBTL1 (0.54) | L3MBTL1POLBTDP1HTTALDH1A1 | |
| SCHEMBL19087151 | 0.85 | POLB (0.71) | L3MBTL1POLBTDP1HTTKDM4E | |
| SCHEMBL19116359 | 0.84 | TDP1 (0.70) | L3MBTL1POLBTDP1HTTKDM4E | |
| SCHEMBL2821286 | 0.84 | MEN1 (0.60) | L3MBTL1POLBTDP1HTTKDM4E | |
| SCHEMBL30730185 | 0.83 | POLB (0.62) | L3MBTL1POLBTDP1HTTKDM4E | |
| SCHEMBL27286142 | 0.83 | HSD17B10 (0.68) | L3MBTL1POLBTDP1HTTKDM4E | |
| SCHEMBL19087148 | 0.83 | POLB (0.68) | L3MBTL1POLBTDP1HTTKDM4E | |
| SCHEMBL15154988 | 0.82 | L3MBTL1 (0.60) | L3MBTL1POLBTDP1HTTKDM4E | |
| SCHEMBL4017203 | 0.82 | L3MBTL1 (0.60) | L3MBTL1POLBTDP1HTTKDM4E | |
| SCHEMBL13851465 | 0.82 | TDP1 (1.00) | L3MBTL1POLBTDP1HTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024026483-A2 | CDK2 INHIBITORS AND METHODS OF USING THE SAME | CEDILLA THERAPEUTICS, INC. (US) | 2024-02-01 | — | — | WO | disclosed |