Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | KLKB1 | P03952 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | USP2 | O75604 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1912400 | 0.91 | HSD17B10 (0.77) | HSD17B10L3MBTL1POLBTDP1ALDH1A1 | |
| SCHEMBL13692389 | 0.88 | L3MBTL1 (0.54) | HSD17B10L3MBTL1POLBTDP1ALDH1A1 | |
| SCHEMBL19300037 | 0.88 | HSD17B10 (0.51) | HSD17B10L3MBTL1POLBTDP1ALDH1A1 | |
| SCHEMBL27364232 | 0.86 | KLKB1 (0.53) | HSD17B10POLBALDH1A1KDM4EKLKB1 | |
| SCHEMBL17229366 | 0.86 | KLKB1 (0.51) | HSD17B10L3MBTL1POLBTDP1ALDH1A1 | |
| SCHEMBL752774 | 0.85 | LMNA (0.61) | HSD17B10ALDH1A1KDM4EKLKB1MEN1 | |
| SCHEMBL19087149 | 0.83 | HSD17B10 (0.70) | HSD17B10L3MBTL1POLBTDP1ALDH1A1 | |
| SCHEMBL948453 | 0.83 | HSD17B10 (0.61) | HSD17B10L3MBTL1POLBTDP1ALDH1A1 | |
| SCHEMBL27259482 | 0.83 | KLKB1 (0.51) | HSD17B10L3MBTL1POLBTDP1ALDH1A1 | |
| SCHEMBL27364039 | 0.83 | L3MBTL1 (0.70) | HSD17B10L3MBTL1POLBTDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024026486-A2 | CDK2 INHIBITORS AND METHODS OF USING THE SAME | CEDILLA THERAPEUTICS, INC. (US) | 2024-02-01 | — | — | WO | disclosed |
| WO-2024026484-A2 | CDK2 INHIBITORS AND METHODS OF USING THE SAME | CEDILLA THERAPEUTICS, INC. (US) | 2024-02-01 | — | — | WO | disclosed |
| WO-2024026483-A2 | CDK2 INHIBITORS AND METHODS OF USING THE SAME | CEDILLA THERAPEUTICS, INC. (US) | 2024-02-01 | — | — | WO | disclosed |