SCHEMBL584613

SCHEMBL584613

Nc1ccn([C@@H]2O[C@H](CO[P](=O)O)[C@@H](O)[C@H]2O)c(=O)n1

nearest known ligand 0.70

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.70
THRB P10828 1/20 0.70
MTOR P42345 1/20 0.70
MDM2 Q00987 1/20 0.70
NCOA1 Q15788 1/20 0.70
NCOA3 Q9Y6Q9 1/20 0.70
L3MBTL1 Q9Y468 1/20 0.58
TSHR P16473 1/20 0.57
GLA P06280 1/20 0.57
P2RY2 P41231 1/20 0.57
ST6GAL1 P15907 7/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7026416 0.92 LMNA (0.72) LMNATHRBMTORMDM2NCOA1
SCHEMBL28403435 0.92 LMNA (0.72) LMNATHRBMTORMDM2NCOA1
SCHEMBL338709 0.91 LMNA (0.70) LMNATHRBMTORMDM2NCOA1
SCHEMBL5491562 0.87 LMNA (0.75) LMNATHRBMTORMDM2NCOA1
SCHEMBL366600 0.87 LMNA (0.75) LMNATHRBMTORMDM2NCOA1
SCHEMBL4946508 0.87 LMNA (0.75) LMNATHRBMTORMDM2NCOA1
SCHEMBL27364585 0.86 LMNA (0.61) LMNATHRBMTORMDM2NCOA1
SCHEMBL17304691 0.86 LMNA (0.73) LMNATHRBMTORMDM2NCOA1
SCHEMBL2811458 0.86 LMNA (0.73) LMNATHRBMTORMDM2NCOA1
SCHEMBL13524621 0.86 LMNA (0.73) LMNATHRBMTORMDM2NCOA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1994014981-A1 TREATMENT OF VIRAL INFECTIONS CHEN ROLLAND (US) 1994-07-07 WO claimed
JP-9107965-A None JP disclosed
US-20240226188-A9 COMPOSITIONS COMPRISING ANIMAL HEMOGLOBIN EVELO BIOSCIENCES, INC. 2024-07-11 US disclosed
CN-114630911-B Enzymatic process for the preparation of UDP-GlcNAc 马克斯·普朗克科学促进学会 2024-06-28 CN disclosed
US-20240131083-A1 COMPOSITIONS COMPRISING ANIMAL HEMOGLOBIN EVELO BIOSCIENCES INC (US) 2024-04-25 US disclosed
CN-117120060-A Aqueous solutions containing purines and pyrimidines and use thereof 周格尼克斯-莫迪斯公司 2023-11-24 CN disclosed
US-20230340116-A1 THERAPEUTIC AND DIAGNOSTIC METHODS RELATING TO CANCER STEM CELLS CHILDREN'S MEDICAL CENTER CORPORATION (US) 2023-10-26 US disclosed
CN-114641577-B Enzymatic process for the preparation of UDP-galactose 马克斯·普朗克科学促进学会 2023-06-23 CN disclosed
CN-113748212-B Enzymatic process for preparing GDP-fucose 马克斯·普朗克科学促进学会 2023-04-25 CN disclosed
US-20230090600-A1 MICROBIAL FERMENTATION FOR THE PRODUCTION OF ISOPRENOID ALCOHOLS AND DERIVATIVES LANZATECH, INC. 2023-03-23 US disclosed
US-6774082-B2 COMPOSITION FOR USE IN THE SEPARATION OF PREFERENTIAL BIOPOLYMERS FROM SAMPLE IBC ADVANCED TECHNOLOGIES, INC. 2004-08-10 US disclosed
WO-2004035614-A1 SYNTHETIC OR PARTIALLY PURIFIED PEPTIDES WHICH CAN BIND TO SPECIFIC SUBUNITS OF G PROTEINS AND USES THEREOF KARO BIO AB (SE) 2004-04-29 WO disclosed
US-20030050458-A1 Compositions and methods for separating heterocyclic aromatic amine bases, nucleosides, nucleotides, and nucleotide sequences IBC ADVANCED TECHNOLOGIES, INC. 2003-03-13 US disclosed
EP-1290004-A1 METHOD OF IDENTIFYING CRITICAL POINTS WITHIN PROTEIN-PROTEIN INTERACTIONS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2003-03-12 EP disclosed
WO-2002092766-A2 COMPOSITIONS AND METHODS FOR SEPARATING HETEROCYCLIC AROMATIC AMINE BASES, NUCLEOSIDES, NUCLEOTIDES, AND NUCLEOTIDE SEQUENCES IBC ADVANCED TECHNOLOGIES, INC. (US) 2002-11-21 WO disclosed
US-6365359-B1 IDENTIFYING PRP PHARMACORE BY DETERMINING FUNCTIONAL RESIDUES OF PROTEIN INVOLVED IN COMPLEX INTERACTIONS, DEVELOPING THREE DIMENSIONAL STRUCTURES, COMPARING THEM WITH OTHER COMPOUNDS AND IDENTIFYING COMPOUNDS CONSISTENT WITH BINDING TO PROTEIN THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2002-04-02 US disclosed
WO-2001087911-A1 METHOD OF IDENTIFYING CRITICAL POINTS WITHIN PROTEIN-PROTEIN INTERACTIONS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2001-11-22 WO disclosed
US-20010023067-A1 Nucleic acid molecules encoding polypeptides having the enzymatic activity of an RNA-directed RNA polymerase (RdRP) MICHAEL WASSENEGGER AND LEONHARD RIEDEL 2001-09-20 US disclosed
US-6218142-B1 NUCLEOTIDE AND AMINO ACID SEQUENCE; RECOMBINANT CULTURE PRODUCTION; ANTIBODIES; ANTAGONISTS; TRANSGENIC PLANT CELLS; DIAGNOSIS; KITS Wassenegger, Michael (DE) 2001-04-17 US disclosed
JP-H09107965-A PRODUCTION OF ACYLNOYLAMINATE CYTIDYLYL TRANSFERASE KOHJIN CO LTD 1997-04-28 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030050458-A1 Compositions and methods for separating heterocyclic aromatic amine bases, nucleosides, nucleotides, and nucleotide sequences NUDT1, ATIC, PNP LMNA 1739/4885THRB 4461/4885MTOR 4009/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.