Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.72 |
| ▸ | THRB | P10828 | 1/20 | 0.72 |
| ▸ | MTOR | P42345 | 1/20 | 0.72 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.72 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.72 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.72 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | GLA | P06280 | 1/20 | 0.58 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.58 |
| ▸ | ST6GAL1 | P15907 | 6/20 | 0.55 |
| ▸ | NT5E | P21589 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28403435 | 1.00 | LMNA (0.72) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL338709 | 0.92 | LMNA (0.70) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL584613 | 0.92 | LMNA (0.70) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL366600 | 0.88 | LMNA (0.75) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL4946508 | 0.88 | LMNA (0.75) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL5491562 | 0.88 | LMNA (0.75) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL17304691 | 0.87 | LMNA (0.73) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL2811458 | 0.87 | LMNA (0.73) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL13524621 | 0.87 | LMNA (0.73) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL383499 | 0.87 | LMNA (0.73) | LMNATHRBMTORMDM2NCOA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6518418-B1 | Nucleotide sugars | THE SCRIPPS RESEARCH INSTITUTE | 2003-02-11 | — | — | US | disclosed |