Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 2/20 | 0.32 |
| ▸ | BRD2 | P25440 | 2/20 | 0.32 |
| ▸ | BRD9 | Q9H8M2 | 2/20 | 0.32 |
| ▸ | BRD7 | Q9NPI1 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.31 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.30 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.30 |
| ▸ | NQO2 | P16083 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2736607 | 0.77 | CYP19A1 (0.35) | ALDH1A1L3MBTL1KDM4EHPGDCYP19A1 | |
| SCHEMBL19197220 | 0.75 | BRD4 (0.42) | ALDH1A1BRD4BRD2BRD9BRD7 | |
| SCHEMBL2736488 | 0.70 | BRD4 (0.33) | ALDH1A1BRD4BRD2BRD9BRD7 | |
| SCHEMBL2736479 | 0.70 | DAO (0.46) | ALDH1A1BRD4BRD2BRD9BRD7 | |
| SCHEMBL15975183 | 0.70 | GRIA1 (0.36) | ALDH1A1BRD4BRD2BRD9BRD7 | |
| SCHEMBL2736524 | 0.70 | ATAD2 (0.45) | ALDH1A1BRD4BRD2BRD9BRD7 | |
| SCHEMBL2736480 | 0.68 | CYP19A1 (0.46) | L3MBTL1BRD4BRD2BRD9BRD7 | |
| SCHEMBL22016198 | 0.67 | CRHR1 (0.38) | ALDH1A1BRD4BRD2BRD9BRD7 | |
| SCHEMBL22017498 | 0.66 | DAO (0.59) | ALDH1A1L3MBTL1BRD4BRD9KDM4E | |
| SCHEMBL3372808 | 0.66 | ALDH1A1 (0.38) | ALDH1A1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8088924-B2 | Pyridone derivatives having a binding activity to the cannabinoid type 2 receptor | SHIONOGI & CO., LTD. (JP) | 2012-01-03 | — | — | US | disclosed |
| US-20100081686-A1 | Pyridone derivatives having a binding activity to the cannabinoid type 2 recepter | TADA YUKIO | 2010-04-01 | — | — | US | disclosed |
| US-20080312292-A1 | Antipruritics | YASUI KIYOSHI | 2008-12-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100081686-A1 | Pyridone derivatives having a binding activity to the cannabinoid type 2 recepter | CNR2, CNR1, NPY2R | ALDH1A1 3078/4885L3MBTL1 4225/4885BRD4 152/4885 |
| US-20080312292-A1 | Antipruritics | CNR1, CNR2, OPRL1 | ALDH1A1 3580/4885L3MBTL1 3630/4885BRD4 446/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.