Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27680708 | 0.94 | HSD17B10 (0.35) | HCAR2HSD17B10ALDH1A1MAPTHPGD | |
| SCHEMBL817864 | 0.80 | ALDH1A1 (0.39) | HSD17B10ALDH1A1HPGDSMN1; SMN2LMNA | |
| SCHEMBL819348 | 0.76 | SMN1; SMN2 (0.44) | HSD17B10ALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL11830551 | 0.75 | HCAR2 (0.35) | HCAR2HSD17B10ALDH1A1MAPK1HPGD | |
| SCHEMBL10405114 | 0.74 | HSD17B10 (0.38) | HCAR2HSD17B10ALDH1A1MAPTMAPK1 | |
| SCHEMBL18468384 | 0.73 | TSHR (0.32) | HSD17B10ALDH1A1HPGDSMN1; SMN2TSHR | |
| SCHEMBL22810807 | 0.72 | GRM1 (0.35) | HCAR2ALDH1A1LMNAESR1CHRM1 | |
| SCHEMBL16160142 | 0.71 | TSHR (0.37) | ALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL30145015 | 0.71 | HCAR2 (0.41) | HCAR2ALDH1A1SMN1; SMN2LMNAESR1 | |
| Cyclohexane SCHEMBL4366431 | 0.70 | HSD17B10 (0.41) | HSD17B10ALDH1A1L3MBTL1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1200917-C | Process for preparation of cyclopropyl acethlene derivative | KURARAY CO (JP) | 2005-05-11 | — | — | CN | disclosed |
| CN-1183090-C | Method for preparation of cyclopropyl acrylic derivative | �����ɷ� | 2005-01-05 | — | — | CN | disclosed |
| CN-1070833-C | Process for preparing cyclopropyl acetylene derivatives | KURARAY CO (JP) | 2001-09-12 | — | — | CN | disclosed |
| CN-1281846-A | Method for preparation of cyclopropyl acrylic derivative | KURARAY CO (JP) | 2001-01-31 | — | — | CN | disclosed |
| CN-1281840-A | Process for preparation of cyclopropyl acethlene derivative | KURARAY CO (JP) | 2001-01-31 | — | — | CN | disclosed |
| CN-1191856-A | Process for preparing cyclopropyl acetylene derivatives | KURARAY CO (JP) | 1998-09-02 | — | — | CN | disclosed |