SCHEMBL817864

SCHEMBL817864

CCOC(=O)C(COC)C(C)C

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.39
HSD17B10 Q99714 2/20 0.37
LMNA P02545 1/20 0.37
ALOX15 P16050 3/20 0.36
MGAM O43451 1/20 0.36
GAA P10253 1/20 0.36
SI P14410 1/20 0.36
MGAM2 Q2M2H8 1/20 0.36
SOAT1 P35610 1/20 0.36
TRPA1 O75762 1/20 0.33
CYP3A4 P08684 2/20 0.33
TDP1 Q9NUW8 2/20 0.33
TSHR P16473 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
CHRM1 P11229 1/20 0.32
ADORA1 P30542 1/20 0.32
HPGD P15428 1/20 0.32
PIN1 Q13526 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27680708 0.85 HSD17B10 (0.35) ALDH1A1HSD17B10LMNATDP1TSHR
SCHEMBL819866 0.83 ALDH1A1 (0.39) ALDH1A1HSD17B10LMNAALOX15MGAM
SCHEMBL819348 0.82 SMN1; SMN2 (0.44) ALDH1A1HSD17B10TSHRSMN1; SMN2MEN1
Cyclopropane SCHEMBL27365075 0.80 HCAR2 (0.32) ALDH1A1HSD17B10LMNATDP1TSHR
SCHEMBL17617141 0.79 ALDH1A1 (0.43) ALDH1A1HSD17B10LMNAALOX15MGAM
SCHEMBL13575648 0.79 ALDH1A1 (0.43) ALDH1A1HSD17B10LMNAALOX15MGAM
SCHEMBL2303261 0.79 ALDH1A1 (0.43) ALDH1A1HSD17B10LMNAALOX15MGAM
SCHEMBL18468384 0.79 TSHR (0.32) ALDH1A1HSD17B10TDP1TSHRSMN1; SMN2
SCHEMBL888252 0.79 ALDH1A1 (0.36) ALDH1A1HSD17B10LMNAALOX15MGAM
SCHEMBL12868877 0.77 ALDH1A1 (0.42) ALDH1A1HSD17B10LMNAALOX15MGAM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130190464-A1 PROCESS FOR PRODUCING SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-07-25 US disclosed
US-20130109789-A1 OLEFIN POLYMERIZATION CATALYST, PROCESS FOR PRODUCING OLEFIN POLYMER, POLYPROPYLENE RESIN COMPOSITION AND ARTICLE COMPRISING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-05-02 US disclosed
US-8288488-B2 Process for producing solid catalyst component for olefin polymerization SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-10-16 US disclosed
US-20110269929-A1 PROCESS FOR PRODUCING SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-11-03 US disclosed
US-20110269928-A1 PROCESS FOR PRODUCING SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-11-03 US disclosed