Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.61 |
| ▸ | MAPT | P10636 | 6/20 | 0.61 |
| ▸ | NPC1 | O15118 | 9/20 | 0.51 |
| ▸ | APP | P05067 | 5/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.50 |
| ▸ | SNCA | P37840 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ACP1 | P24666 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.42 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28015679 | 0.84 | SMN1; SMN2 (0.51) | RAB9AMAPTNPC1APPKDM4E | |
| SCHEMBL28015160 | 0.79 | RAB9A (0.65) | RAB9AMAPTNPC1APPKDM4E | |
| SCHEMBL30542465 | 0.79 | SMN1; SMN2 (0.66) | RAB9AMAPTNPC1APPKDM4E | |
| SCHEMBL84327 | 0.79 | SMN1; SMN2 (0.66) | RAB9AMAPTNPC1APPKDM4E | |
| SCHEMBL13444809 | 0.79 | MAPT (0.69) | RAB9AMAPTNPC1APPKDM4E | |
| SCHEMBL1638573 | 0.78 | RAB9A (0.63) | RAB9AMAPTNPC1APPKDM4E | |
| SCHEMBL8620472 | 0.77 | RAB9A (0.58) | RAB9AMAPTNPC1APPKDM4E | |
| SCHEMBL25165513 | 0.76 | RAB9A (0.61) | RAB9AMAPTNPC1APPKDM4E | |
| SCHEMBL10435968 | 0.76 | RAB9A (0.61) | RAB9AMAPTNPC1APPKDM4E | |
| SCHEMBL780451 | 0.76 | RAB9A (0.61) | RAB9AMAPTNPC1APPKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102532162-B | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles | OTSUKA PHARMA CO LTD | 2015-05-27 | — | — | CN | disclosed |
| CN-1067064-C | N-(4-fluoro-phenyl)-heteroaryloxyacetamides | BAYER AG (DE) | 2001-06-13 | — | — | CN | disclosed |
| CN-1102646-A | N-(4-fluoro-phenyl)-heteroaryloxyacetamides | BAYER AG (DE) | 1995-05-17 | — | — | CN | disclosed |