Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 6/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | NQO2 | P16083 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 5/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.39 |
| ▸ | RELA | Q04206 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27365085 | 0.84 | RAB9A (0.61) | SMN1; SMN2MAPTTP53DYRK1ARAB9A | |
| SCHEMBL92781 | 0.79 | SMN1; SMN2 (0.61) | SMN1; SMN2MAPTTP53DYRK1ARAB9A | |
| Bromide SCHEMBL10996884 | 0.78 | SMN1; SMN2 (0.59) | SMN1; SMN2MAPTTP53DYRK1ARAB9A | |
| SCHEMBL9305718 | 0.78 | SMN1; SMN2 (0.53) | SMN1; SMN2MAPTTP53DYRK1ARAB9A | |
| SCHEMBL12262 | 0.76 | MAPT (0.72) | SMN1; SMN2MAPTTP53DYRK1ARAB9A | |
| SCHEMBL30189802 | 0.76 | SMN1; SMN2 (0.51) | SMN1; SMN2MAPTTP53DYRK1ARAB9A | |
| SCHEMBL2749398 | 0.76 | SMN1; SMN2 (0.51) | SMN1; SMN2MAPTTP53DYRK1ARAB9A | |
| SCHEMBL11549599 | 0.76 | DYRK1A (0.54) | SMN1; SMN2MAPTTP53DYRK1ARAB9A | |
| SCHEMBL29572251 | 0.76 | MAPT (0.72) | SMN1; SMN2MAPTTP53DYRK1ARAB9A | |
| SCHEMBL799569 | 0.76 | SMN1; SMN2 (0.51) | SMN1; SMN2MAPTTP53DYRK1ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102532162-B | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles | OTSUKA PHARMA CO LTD | 2015-05-27 | — | — | CN | disclosed |