Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.45 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27529448 | 0.89 | MAPT (0.40) | HDAC8HDAC11CACNA1BFFAR1HDAC1 | |
| SCHEMBL27362585 | 0.88 | MEN1 (0.42) | HDAC8HDAC11CACNA1BFFAR1ADRA2A | |
| SCHEMBL27379179 | 0.84 | TSHR (0.39) | ALDH1A1LMNATSHR | |
| SCHEMBL9484705 | 0.81 | CACNA1B (0.49) | HDAC8HDAC11CACNA1BFFAR1ALDH1A1 | |
| SCHEMBL27389629 | 0.77 | NPC1 (0.36) | ALDH1A1LMNATSHR | |
| SCHEMBL27370386 | 0.77 | ALDH1A1 (0.37) | HDAC6ADRA2AMEN1ALDH1A1LMNA | |
| SCHEMBL27382619 | 0.75 | HTR2A (0.39) | MEN1ALDH1A1LMNAPOLBMAPT | |
| SCHEMBL1520656 | 0.74 | FFAR1 (0.55) | HDAC8FFAR1HDAC1HDAC6TSHR | |
| SCHEMBL27361074 | 0.74 | ALDH1A1 (0.47) | ADRA2ACNR1ALDH1A1LMNAPOLB | |
| SCHEMBL28194680 | 0.74 | ALDH1A1 (0.47) | ADRA2ACNR1ALDH1A1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1056494-A | The bis-aryl amide of platelet activating factor and urea antagonists | AMERICAN CYANAMID CO (US) | 1991-11-27 | — | — | CN | disclosed |