Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | PLK1 | P53350 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27529448 | 0.92 | MAPT (0.40) | MEN1KMT2ACACNA1BHDAC11HDAC8 | |
| SCHEMBL27365324 | 0.88 | HDAC8 (0.45) | MEN1KMT2ACACNA1BHDAC11HDAC8 | |
| SCHEMBL28194680 | 0.83 | ALDH1A1 (0.47) | CYP3A4NPC1ALDH1A1MAPTRAB9A | |
| SCHEMBL27361074 | 0.83 | ALDH1A1 (0.47) | CYP3A4NPC1ALDH1A1MAPTRAB9A | |
| SCHEMBL27382619 | 0.81 | HTR2A (0.39) | MEN1CYP3A4KMT2ANPC1ALDH1A1 | |
| SCHEMBL27360513 | 0.79 | HDAC3 (0.58) | — | |
| SCHEMBL9309140 | 0.79 | CACNA1B (0.58) | MEN1KMT2ACACNA1BMAPTHRH3 | |
| SCHEMBL27362587 | 0.77 | NR5A1 (0.51) | CYP1A2CYP3A4CYP2C19NPC1ALDH1A1 | |
| SCHEMBL27379186 | 0.76 | ALDH1A1 (0.44) | MEN1CYP3A4KMT2ANPC1ALDH1A1 | |
| SCHEMBL3426470 | 0.75 | PLK1 (0.61) | MEN1CYP1A2CYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1069025-A | The aryl of platelet activating factor, acid amides, imide and carbamate pyridine antagonists | AMERICAN CYANAMID CO (US) | 1993-02-17 | — | — | CN | disclosed |