Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9499202 | 0.75 | CHRNB2 (0.50) | CHRNB2CHRNA4LMNACHRM2CHRM4 | |
| SCHEMBL989411 | 0.75 | — | — | |
| SCHEMBL722436 | 0.72 | ALDH1A1 (0.44) | LMNA | |
| SCHEMBL9568968 | 0.71 | QDPR (0.40) | — | |
| SCHEMBL23418849 | 0.68 | TSHR (0.36) | LMNACHRM3 | |
| SCHEMBL2995496 | 0.66 | MAPK1 (0.33) | — | |
| SCHEMBL22142424 | 0.63 | NOTUM (0.39) | CHRNB2CHRNA4NOTUM | |
| SCHEMBL3623103 | 0.62 | — | — | |
| SCHEMBL14340659 | 0.59 | QDPR (0.38) | — | |
| SCHEMBL28373304 | 0.59 | KDM4E (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024054766-A2 | MITOCHONDRIAL UNCOUPLERS FOR TREATMENT OF METABOLIC DISEASES AND CANCER | MITO BIOPHARMA, LLC (US) | 2024-03-14 | — | — | WO | disclosed |