Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26998806 | 0.85 | HPGD (0.59) | HPGDKMT2AALDH1A1TSHRMEN1 | |
| SCHEMBL10747742 | 0.83 | HPGD (0.78) | HPGDKMT2AALDH1A1TSHRNPC1 | |
| SCHEMBL1504239 | 0.82 | MEN1 (0.60) | HPGDKMT2AALDH1A1TSHRNPC1 | |
| SCHEMBL28709820 | 0.82 | KMT2A (0.69) | KMT2AALDH1A1TSHRMAPTLMNA | |
| SCHEMBL5550015 | 0.82 | TSHR (0.55) | HPGDKMT2AALDH1A1TSHRRAB9A | |
| SCHEMBL23932815 | 0.81 | KMT2A (0.73) | HPGDKMT2AALDH1A1TSHRNPC1 | |
| SCHEMBL11188238 | 0.81 | HPGD (0.68) | HPGDKMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL11516939 | 0.81 | RAB9A (0.54) | HPGDKMT2AALDH1A1TSHRNPC1 | |
| SCHEMBL5820518 | 0.81 | L3MBTL1 (0.73) | HPGDKMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL679125 | 0.81 | TSHR (0.69) | HPGDALDH1A1TSHRMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024059878-A9 | DRUGS TARGETING TELOMERASE REVERSE TRANSCRIPTASE (TERT) FOR TREATMENT OF CANCERS | BROWN UNIVERSITY (US) | 2024-07-04 | — | — | WO | disclosed |