Sugi Predict

Sugi Predict / Compounds / SCHEMBL1504239

SCHEMBL1504239

SCHEMBL1504239

CCOC(=O)CC(=O)Nc1cccc(Cl)c1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 4/20 0.60
▸ KMT2A Q03164 4/20 0.60
▸ HPGD P15428 2/20 0.60
▸ TRPV1 Q8NER1 1/20 0.60
▸ EPHX2 P34913 1/20 0.58
▸ MAPT P10636 6/20 0.56
▸ ALDH1A1 P00352 4/20 0.56
▸ HSD17B10 Q99714 2/20 0.56
▸ POLB P06746 1/20 0.56
▸ MAOA P21397 1/20 0.56
▸ MAOB P27338 1/20 0.56
▸ TSHR P16473 1/20 0.55
▸ LMNA P02545 3/20 0.55
▸ SMN1; SMN2 Q16637 2/20 0.55
▸ EGFR P00533 1/20 0.55
▸ HTT P42858 2/20 0.54
▸ GAA P10253 1/20 0.53
▸ KDM4E B2RXH2 2/20 0.53
▸ MAPK1 P28482 2/20 0.53
▸ L3MBTL1 Q9Y468 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21723671 0.95 MEN1 (0.55) MEN1KMT2AHPGDTRPV1EPHX2
SCHEMBL15988002 0.88 MEN1 (0.61) MEN1KMT2AHPGDTRPV1MAPT
SCHEMBL26998806 0.85 HPGD (0.59) MEN1KMT2AHPGDALDH1A1HSD17B10
SCHEMBL8880319 0.84 L3MBTL1 (0.59) MEN1KMT2AHPGDMAPTALDH1A1
SCHEMBL1189665 0.83 MAPT (0.66) MEN1KMT2AHPGDTRPV1EPHX2
SCHEMBL30599557 0.83 MAPT (0.66) MEN1KMT2AHPGDTRPV1EPHX2
SCHEMBL5550015 0.82 TSHR (0.55) MEN1KMT2AHPGDMAPTALDH1A1
SCHEMBL28709820 0.82 KMT2A (0.69) MEN1KMT2AMAPTALDH1A1POLB
SCHEMBL27365595 0.82 HPGD (0.59) MEN1KMT2AHPGDMAPTALDH1A1
SCHEMBL5141417 0.82 MEN1 (0.71) MEN1KMT2AHPGDEPHX2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12371429-B2 Antibiotic resistance-modifying tricyclic heteroaryl compounds and uses thereof RECREO PHARMACEUTICALS LLC (US) 2025-07-29 — — US disclosed
CN-116693531-A Synthesis method of bridged polycyclic lactam compound 河南师范大学 2023-09-05 — — CN disclosed
US-20210163479-A1 1,3,4,9-TETRAHYDRO-2H-PYRIDO[3,4-B]INDOLE DERIVATIVE COMPOUNDS AND USES THEREOF RECREO PHARMACEUTICALS LLC (US) 2021-06-03 — — US disclosed
US-20210163479-A1 1,3,4,9-TETRAHYDRO-2H-PYRIDO[3,4-B]INDOLE DERIVATIVE COMPOUNDS AND USES THEREOF RECREO PHARMACEUTICALS LLC (US) 2021-06-03 — — US disclosed
CN-112654354-A 1,3,4, 9-tetrahydro-2H-pyrido [3,4-b ] indole derivative compound and application thereof 菲尼克思药业股份有限公司 2021-04-13 — — CN disclosed
WO-2020037155-A1 1,3,4,9-TETRAHYDRO-2H-PYRIDO[3,4-B]INDOLE DERIVATIVE COMPOUNDS AND USES THEREOF RECREO PHARMACEUTICALS LLC (US) 2020-02-20 — — WO disclosed
EP-1405852-B9 DIAMINE DERIVATIVES DAIICHI SANKYO CO LTD (JP) 2013-03-27 — — EP disclosed
EP-1405852-B9 DIAMINE DERIVATIVES DAIICHI SANKYO CO LTD (JP) 2013-03-27 — — EP disclosed
CN-1826333-B Diamine derivatives DAIICHI SANKYO CO LTD 2012-12-26 — — CN disclosed
EP-1577301-B1 Antithrombotic diaminocyclohexane derivatives DAIICHI SANKYO CO LTD (JP) 2012-09-12 — — EP disclosed
CN-1826333-A Diamine derivatives DAIICHI SEIYAKU CO (JP) 2006-08-30 — — CN disclosed
CN-1751025-A Diamine derivatives DAIICHI SEIYAKU CO (JP) 2006-03-22 — — CN disclosed
CN-1745071-A Novel ethylenediamine derivative DAIICHI SEIYAKU CO (JP) 2006-03-08 — — CN disclosed
US-20050245565-A1 Diamine derivatives DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2005-11-03 — — US disclosed
EP-1577301-A1 DIAMINE DERIVATIVES DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2005-09-21 — — EP disclosed
EP-1577302-A1 NOVEL ETHYLENEDIAMINE DERIVATIVES DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2005-09-21 — — EP disclosed
US-20050119486-A1 Diamine derivatives DAIICHI SANKYO COMPANY, LIMITED (JP) 2005-06-02 — — US disclosed
US-20050020645-A1 Diamine derivatives DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2005-01-27 — — US disclosed
EP-1415992-A1 DIAMINE DERIVATIVES DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2004-05-06 — — EP disclosed
EP-1405852-A1 DIAMINE DERIVATIVES DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2004-04-07 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12371429-B2 Antibiotic resistance-modifying tricyclic heteroaryl compounds and uses thereof CBR3, CBR1, CYP2B6 MEN1 1968/4885KMT2A 1544/4885HPGD 3554/4885
US-20050020645-A1 Diamine derivatives C9, C1S, C1R MEN1 457/4885KMT2A 3485/4885HPGD 2022/4885
US-20050245565-A1 Diamine derivatives C9, C1S, C1R MEN1 457/4885KMT2A 3485/4885HPGD 2022/4885
US-20050119486-A1 Diamine derivatives C9, C1S, C1R MEN1 457/4885KMT2A 3485/4885HPGD 2022/4885
US-20210163479-A1 1,3,4,9-TETRAHYDRO-2H-PYRIDO[3,4-B]INDOLE DERIVATIVE COMPOUNDS AND USES THEREOF H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, CCNA1, FOXM1 MEN1 1942/4885KMT2A 1984/4885HPGD 2568/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.