Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 9/20 | 0.50 |
| ▸ | HSD17B2 | P37059 | 9/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL27347184 | 0.98 | HSD17B1 (0.51) | HSD17B1HSD17B2SIGMAR1ALDH1A1NPC1 | |
| SCHEMBL30229852 | 0.91 | HSD17B1 (0.57) | HSD17B1HSD17B2SIGMAR1ALDH1A1NPC1 | |
| SCHEMBL1684295 | 0.91 | HSD17B1 (0.57) | HSD17B1HSD17B2SIGMAR1ALDH1A1NPC1 | |
| Ammonia Solution, Strong SCHEMBL28786422 | 0.90 | HSD17B1 (0.55) | HSD17B1HSD17B2SIGMAR1ALDH1A1NPC1 | |
| Piperazine SCHEMBL27719282 | 0.82 | HSD17B1 (0.49) | HSD17B1HSD17B2SIGMAR1ALDH1A1NPC1 | |
| Pyridine SCHEMBL27855919 | 0.82 | HSD17B1 (0.49) | HSD17B1HSD17B2SIGMAR1ALDH1A1NPC1 | |
| SCHEMBL8755598 | 0.79 | POLB (0.51) | HSD17B1HSD17B2KMT2ASMN1; SMN2 | |
| SCHEMBL27347182 | 0.78 | HSD17B1 (0.49) | HSD17B1HSD17B2SIGMAR1ALDH1A1LMNA | |
| SCHEMBL21870620 | 0.77 | HSD17B1 (0.54) | HSD17B1HSD17B2SIGMAR1ALDH1A1NPC1 | |
| SCHEMBL28007816 | 0.77 | HSD17B1 (0.48) | HSD17B1HSD17B2SIGMAR1ALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1053085-C | Composition for killing snail | ZHAO XIAOWU (CN) | 2000-06-07 | — | — | CN | claimed |
| CN-1698437-A | Pesticide for preventing mollusks such as snail and slug | ZHAO XIAOWU (CN) | 2005-11-23 | — | — | CN | disclosed |
| CN-1053085-C | Composition for killing snail | ZHAO XIAOWU (CN) | 2000-06-07 | — | — | CN | disclosed |