Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | HSD17B1 | P14061 | 4/20 | 0.49 |
| ▸ | HSD17B2 | P37059 | 4/20 | 0.49 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | VNN1 | O95497 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30229852 | 0.86 | HSD17B1 (0.57) | HSD17B1HSD17B2SMN1; SMN2TDP1 | |
| SCHEMBL1684295 | 0.86 | HSD17B1 (0.57) | HSD17B1HSD17B2SMN1; SMN2TDP1 | |
| Ammonia Solution, Strong SCHEMBL28786422 | 0.84 | HSD17B1 (0.55) | HSD17B1HSD17B2SMN1; SMN2TDP1 | |
| SCHEMBL29503529 | 0.80 | PARP1 (0.68) | POLBPARP1SMN1; SMN2CNR2TDP1 | |
| SCHEMBL186545 | 0.80 | PARP1 (0.68) | POLBPARP1SMN1; SMN2CNR2TDP1 | |
| Sulfuric Acid SCHEMBL27347184 | 0.80 | HSD17B1 (0.51) | HSD17B1HSD17B2SMN1; SMN2KMT2A | |
| SCHEMBL28654162 | 0.80 | POLB (0.49) | POLBHSD17B1HSD17B2PARP1SMN1; SMN2 | |
| SCHEMBL28007816 | 0.79 | HSD17B1 (0.48) | HSD17B1HSD17B2PARP1SMN1; SMN2TDP1 | |
| Sulfuric Acid SCHEMBL27365736 | 0.79 | HSD17B1 (0.50) | HSD17B1HSD17B2SMN1; SMN2KMT2A | |
| SCHEMBL81347 | 0.79 | ATM (0.71) | POLBPARP1SMN1; SMN2CNR2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0628542-B1 | Process for the preparation of organic carbamates | BAYER AG (DE) | 1997-04-09 | — | — | EP | disclosed |
| EP-0628542-A1 | Process for the preparation of organic carbonates | BAYER AG (DE) | 1994-12-14 | — | — | EP | disclosed |