Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.46 |
| ▸ | KLK1 | P06870 | 4/20 | 0.46 |
| ▸ | TMPRSS2 | O15393 | 2/20 | 0.46 |
| ▸ | F2 | P00734 | 3/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.46 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.46 |
| ▸ | HPN | P05981 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.46 |
| ▸ | HGFAC | Q04756 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | SLC47A2 | Q86VL8 | 1/20 | 0.46 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22193385 | 0.85 | PRSS1 (0.52) | CA2POLBPRSS1KMT2AALDH1A1 | |
| SCHEMBL12895869 | 0.83 | SMN1; SMN2 (0.57) | CA2POLBPRSS1KLK1TMPRSS2 | |
| SCHEMBL21318232 | 0.83 | SMN1; SMN2 (0.57) | CA2PRSS1KMT2AALDH1A1PKM | |
| SCHEMBL10468377 | 0.82 | HRH3 (0.54) | POLBALDH1A1LSSSMN1; SMN2TSHR | |
| SCHEMBL9837043 | 0.82 | KMT2A (0.65) | PRSS1KMT2AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL18874037 | 0.76 | MAPT (0.49) | POLBPRSS1KLK1TMPRSS2KMT2A | |
| SCHEMBL13113438 | 0.75 | ALDH1A1 (0.44) | POLBKMT2AALDH1A1LSSSMN1; SMN2 | |
| SCHEMBL22166798 | 0.75 | THRB (0.50) | POLBPRSS1KLK1TMPRSS2KMT2A | |
| SCHEMBL26047455 | 0.74 | KMT2A (0.52) | PRSS1KLK1TMPRSS2F2PRSS2 | |
| SCHEMBL6231216 | 0.74 | HRH3 (0.49) | KMT2AALDH1A1LSSSMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1065866-A | The prodrug esters of phenol 2-piperidino-(1-position only)-1-alkanol | PFIZER (US) | 1992-11-04 | — | — | CN | disclosed |