SCHEMBL21318232

SCHEMBL21318232

CN(C)Cc1ccc(C(=O)Oc2ccccc2)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.57
MAPT P10636 2/20 0.57
ALDH1A1 P00352 3/20 0.55
KMT2A Q03164 3/20 0.55
PKM P14618 1/20 0.55
TSHR P16473 2/20 0.50
PARP10 Q53GL7 1/20 0.50
TMPRSS15 P98073 2/20 0.49
ACHE P22303 1/20 0.49
PRSS1 P07477 1/20 0.49
ACR P10323 1/20 0.49
TAAR1 Q96RJ0 1/20 0.49
CA2 P00918 1/20 0.48
TDP1 Q9NUW8 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
NSD2 O96028 1/20 0.46
MEN1 O00255 2/20 0.45
NPC1 O15118 1/20 0.45
RAB9A P51151 1/20 0.45
HPGD P15428 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22193385 0.86 PRSS1 (0.52) MAPTALDH1A1KMT2APKMPARP10
SCHEMBL27365841 0.83 CA2 (0.48) SMN1; SMN2MAPTALDH1A1KMT2APKM
SCHEMBL5706102 0.83 RAB9A (0.57) SMN1; SMN2MAPTALDH1A1KMT2APKM
SCHEMBL70034 0.80 PARP10 (0.70) SMN1; SMN2MAPTALDH1A1KMT2APKM
SCHEMBL9837043 0.80 KMT2A (0.65) SMN1; SMN2MAPTALDH1A1KMT2APRSS1
SCHEMBL5081701 0.80 PARP10 (0.56) SMN1; SMN2MAPTALDH1A1KMT2APKM
SCHEMBL26038913 0.80 PARP10 (0.56) SMN1; SMN2MAPTALDH1A1KMT2APKM
SCHEMBL9837067 0.79 ALDH1A1 (0.70) SMN1; SMN2MAPTALDH1A1KMT2ATSHR
SCHEMBL3771392 0.79 KMT2A (0.56) SMN1; SMN2MAPTALDH1A1KMT2APKM
SCHEMBL8983809 0.78 CES2 (0.59) SMN1; SMN2MAPTALDH1A1KMT2APKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190270904-A1 PIGMENT DISPERSION LIQUID, CURABLE COMPOSITION, FILM, NEAR INFRARED CUT FILTER, SOLID-STATE IMAGING ELEMENT, IMAGE DISPLAY DEVICE, AND INFRARED SENSOR FUJIFILM CORPORATION (JP) 2019-09-05 US disclosed