SCHEMBL27366565

SCHEMBL27366565

OCCc1cccc2cccc(O)c12

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 4/20 0.62
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
ALDH1A1 P00352 2/20 0.43
DNMT1 P26358 1/20 0.43
CACNA1B Q00975 1/20 0.43
APBA1 Q02410 1/20 0.43
MCL1 Q07820 1/20 0.43
APOBEC3G Q9HC16 1/20 0.43
HSPA5 P11021 1/20 0.38
TAAR1 Q96RJ0 1/20 0.38
CDK2 P24941 1/20 0.37
TSHR P16473 3/20 0.37
CYP1A2 P05177 2/20 0.37
HPGD P15428 2/20 0.37
HSD17B10 Q99714 2/20 0.37
MAPT P10636 2/20 0.37
APP P05067 1/20 0.37
THRB P10828 1/20 0.37
ALOX15 P16050 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10339351 0.87 HTR2A (0.46) HTR2AMEN1KMT2AALDH1A1TSHR
SCHEMBL2313474 0.85 ALDH1A1 (0.46) HTR2AMEN1KMT2AALDH1A1TSHR
SCHEMBL8402119 0.83 HTR2A (0.56) HTR2AMEN1KMT2AALDH1A1DNMT1
SCHEMBL7930885 0.81 HTR2A (0.42) HTR2AMEN1KMT2AALDH1A1APOBEC3G
SCHEMBL2310354 0.79 CYP1A2 (0.43) HTR2AMEN1KMT2AALDH1A1CDK2
SCHEMBL23043093 0.78 HTR2A (0.40) HTR2AMEN1KMT2AALDH1A1TAAR1
SCHEMBL29876215 0.78 HTR2A (0.40) HTR2AMEN1KMT2AALDH1A1TAAR1
SCHEMBL27366008 0.77 HTR2A (1.00) HTR2ATAAR1HTR2C
SCHEMBL3960209 0.77 HTR2A (0.59) HTR2AMEN1KMT2AALDH1A1DNMT1
SCHEMBL15345310 0.77 HTR2A (0.55) HTR2AMEN1KMT2AALDH1A1DNMT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250333371-A1 COMPOUNDS Psylo Pty Ltd (AU) 2025-10-30 US disclosed
EP-4532462-A1 COMPOUNDS Psylo Pty Ltd (AU) 2025-04-09 EP disclosed
CN-119384406-A Compounds of formula (I) 赛洛私人有限公司 2025-01-28 CN disclosed
WO-2023230649-A1 COMPOUNDS Psylo Pty Ltd (AU) 2023-12-07 WO disclosed
WO-2023230649-A1 COMPOUNDS Psylo Pty Ltd (AU) 2023-12-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250333371-A1 COMPOUNDS SDHA, PYGB, SLC18A2 HTR2A 225/4885MEN1 1154/4885KMT2A 3007/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.