Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 11/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.37 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.37 |
| ▸ | PDE8B | O95263 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27482671 | 0.93 | POLB (0.42) | PTGER4AKR1C3POLBMAPTPDE8B | |
| SCHEMBL8071411 | 0.91 | UCHL1 (0.39) | PTGER4AKR1C3POLBMAPTAKR1C2 | |
| SCHEMBL8067099 | 0.90 | UCHL1 (0.38) | PTGER4AKR1C3POLBMAPTALDH1A1 | |
| SCHEMBL5509234 | 0.90 | UCHL1 (0.38) | PTGER4AKR1C3POLBMAPTALDH1A1 | |
| SCHEMBL27367023 | 0.87 | POLB (0.41) | PTGER4AKR1C3POLBMAPTP2RX3 | |
| SCHEMBL27386727 | 0.85 | PTGER4 (0.38) | PTGER4AKR1C3POLBMAPTPDE8B | |
| SCHEMBL5515660 | 0.84 | UCHL1 (0.41) | PTGER4POLBMAPTALDH1A1 | |
| SCHEMBL27461114 | 0.82 | PKM (0.42) | PTGER4AKR1C3POLBMAPTPDE8B | |
| SCHEMBL8067119 | 0.81 | SLC5A1 (0.43) | POLBMAPTALDH1A1 | |
| SCHEMBL7827679 | 0.81 | UCHL1 (0.40) | PTGER4POLBMAPTPDE8BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1066148-C | Tricyclic benzazepine compounds | MEIJI SEIKA CO (JP) | 2001-05-23 | — | — | CN | disclosed |
| CN-1190971-A | Tricyclic benzazepine * compounds | MEIJI SEIKA CO (JP) | 1998-08-19 | — | — | CN | disclosed |