Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.36 |
| ▸ | PDE8B | O95263 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27481968 | 0.93 | POLB (0.45) | POLBMAPTALOX15L3MBTL1HSD17B10 | |
| SCHEMBL8067119 | 0.90 | SLC5A1 (0.43) | POLBMAPTALOX15L3MBTL1HSD17B10 | |
| SCHEMBL5516696 | 0.89 | SLC5A1 (0.44) | POLBMAPTHSD17B10MEN1KMT2A | |
| SCHEMBL8069350 | 0.89 | SLC5A1 (0.44) | POLBMAPTHSD17B10MEN1KMT2A | |
| SCHEMBL27366045 | 0.87 | PTGER4 (0.41) | POLBMAPTHSP90AA1HSP90AB1ALDH1A1 | |
| SCHEMBL27369607 | 0.85 | MAPT (0.39) | POLBMAPTALOX15L3MBTL1HSD17B10 | |
| SCHEMBL5515342 | 0.83 | SLC5A1 (0.45) | POLBMAPTALOX15L3MBTL1HSD17B10 | |
| SCHEMBL8071411 | 0.80 | UCHL1 (0.39) | POLBMAPTHSD17B10MEN1KMT2A | |
| SCHEMBL7828627 | 0.80 | SLC5A1 (0.44) | POLBMAPTALOX15L3MBTL1HSD17B10 | |
| SCHEMBL27482671 | 0.80 | POLB (0.42) | POLBMAPTALDH1A1KDM4EAKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1066148-C | Tricyclic benzazepine compounds | MEIJI SEIKA CO (JP) | 2001-05-23 | — | — | CN | disclosed |
| CN-1190971-A | Tricyclic benzazepine * compounds | MEIJI SEIKA CO (JP) | 1998-08-19 | — | — | CN | disclosed |