Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | G6PD | P11413 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | KIF11 | P52732 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6988115 | 0.80 | LMNA (0.42) | KDM4ECASP1HSD17B10MEN1KMT2A | |
| SCHEMBL27384849 | 0.76 | KCNA3 (0.35) | SLC6A2SLC6A4KDM4EHSD17B10MEN1 | |
| SCHEMBL27366257 | 0.71 | SLC6A2 (0.35) | SLC6A2OPRM1OPRL1SLC6A4KDM4E | |
| SCHEMBL9786753 | 0.70 | KDM4E (0.39) | SLC6A2SLC6A4KDM4EMEN1KMT2A | |
| SCHEMBL27406358 | 0.68 | MEN1 (0.34) | SLC6A2OPRM1OPRL1SLC6A4KDM4E | |
| SCHEMBL25460806 | 0.67 | HSD11B1 (0.36) | SLC6A2SLC6A4MEN1KMT2AALDH1A1 | |
| SCHEMBL10509197 | 0.65 | CRBN (0.35) | OPRM1OPRL1KDM4EMEN1KMT2A | |
| SCHEMBL15551744 | 0.64 | SLC6A2 (0.43) | SLC6A2OPRM1OPRL1KDM4EMEN1 | |
| SCHEMBL12248256 | 0.64 | CA12 (0.59) | MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL14804204 | 0.64 | TSHR (0.44) | KDM4EMEN1KMT2AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1067385-C | Novel substituted piperidines useful for the treatment of allergic diseases | MERRELL DOW PHARMA (US) | 2001-06-20 | — | — | CN | disclosed |
| CN-1158612-A | Novel substituted piperidines for the treatment of allergic diseases | MERRELL DOW PHARMA (US) | 1997-09-03 | — | — | CN | disclosed |