Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 4/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | STAT6 | P42226 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27384850 | 0.76 | SLC6A3 (0.37) | MEN1KMT2ATSHRSLC6A3ALDH1A1 | |
| SCHEMBL27366256 | 0.71 | SLC6A2 (0.35) | SLC6A2MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL25460806 | 0.67 | HSD11B1 (0.36) | SLC6A2MEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL6988115 | 0.65 | LMNA (0.42) | MEN1KMT2ATSHRKDM4ELMNA | |
| SCHEMBL27406358 | 0.65 | MEN1 (0.34) | SLC6A2MEN1KMT2ATSHRKDM4E | |
| SCHEMBL27366258 | 0.64 | SMN1; SMN2 (0.32) | — | |
| SCHEMBL15551744 | 0.64 | SLC6A2 (0.43) | SLC6A2MEN1KMT2ATSHRKDM4E | |
| SCHEMBL21742338 | 0.63 | TSHR (0.54) | SLC6A2MEN1KMT2ATSHRKDM4E | |
| SCHEMBL20558406 | 0.63 | OPRM1 (0.42) | SLC6A2MEN1KMT2ATSHRKDM4E | |
| SCHEMBL5960527 | 0.62 | GRIN1 (0.42) | SLC6A2MEN1KMT2AKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1067385-C | Novel substituted piperidines useful for the treatment of allergic diseases | MERRELL DOW PHARMA (US) | 2001-06-20 | — | — | CN | disclosed |
| CN-1158612-A | Novel substituted piperidines for the treatment of allergic diseases | MERRELL DOW PHARMA (US) | 1997-09-03 | — | — | CN | disclosed |