SCHEMBL27366266

SCHEMBL27366266

Cc1cc(C)cc(-c2ncnc(-c3ccc(O)cc3O)n2)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.37
KMT2A Q03164 5/20 0.36
ESR2 Q92731 4/20 0.36
MEN1 O00255 4/20 0.36
ESR1 P03372 3/20 0.36
POLB P06746 3/20 0.35
GAA P10253 3/20 0.35
NPC1 O15118 2/20 0.35
RAB9A P51151 2/20 0.35
GFER P55789 2/20 0.35
HTT P42858 2/20 0.35
KDM4E B2RXH2 1/20 0.35
MAPT P10636 1/20 0.35
NFKB1 P19838 1/20 0.35
NFKB2 Q00653 1/20 0.35
RELA Q04206 1/20 0.35
CNR1 P21554 1/20 0.35
CNR2 P34972 1/20 0.35
MGAM O43451 1/20 0.35
SI P14410 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27542279 0.87 ALOX5 (0.41) ALOX5KMT2AESR2MEN1ESR1
SCHEMBL28020448 0.87 ALOX5 (0.41) ALOX5KMT2AESR2MEN1ESR1
SCHEMBL4438569 0.85 ESR1 (0.46) ALOX5KMT2AESR2MEN1ESR1
SCHEMBL8908993 0.83 ESR2 (0.38) KMT2AESR2MEN1ESR1POLB
SCHEMBL6482000 0.82 ESR2 (0.41) ALOX5KMT2AESR2MEN1ESR1
SCHEMBL2354543 0.81 ESR2 (0.42) KMT2AESR2MEN1ESR1POLB
SCHEMBL28050076 0.81 ELANE (0.41) KMT2AMEN1POLBGAANPC1
SCHEMBL8911208 0.81 ALOX5 (0.56) ALOX5KMT2AESR2MEN1ESR1
SCHEMBL27283713 0.79 RAB9A (0.36) GAANPC1RAB9AHTT
SCHEMBL27916414 0.78 NR5A1 (0.46) KMT2AMEN1GAANPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110536620-A Method for manufacturing articles using foam particles NIKE INNOVATE CV 2019-12-03 CN disclosed
CN-110167381-A Textile and article and process for manufacturing textile and article 耐克创新有限合伙公司 2019-08-23 CN disclosed
CN-110167378-A Textile and article and process for manufacturing textile and article 耐克创新有限合伙公司 2019-08-23 CN disclosed
CN-105579503-A Polyolefin compositions for building materials BASF SE 2016-05-11 CN disclosed
CN-104761815-A Scratch resistant polypropylene BASF PERFORMANCE PRODUCTS LLC 2015-07-08 CN disclosed
CN-102639576-B Method for producing polymer using monomer having piperidine skeleton, and molded article MITSUBISHI RAYON CO 2014-11-12 CN disclosed
CN-102264825-B Method of improving scratch resistance and related products and uses BASF SE 2014-07-02 CN disclosed
CN-1070186-C 2-hydroxyphenyltriazines CIBA SC HOLDING AG (CH) 2001-08-29 CN disclosed
CN-1132862-A Photographic recording material containing UV absorber CIBA GEIGY AG (CH) 1996-10-09 CN disclosed