Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 6/20 | 0.41 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.38 |
| ▸ | BTK | Q06187 | 11/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | TEC | P42680 | 1/20 | 0.36 |
| ▸ | TXK | P42681 | 1/20 | 0.36 |
| ▸ | BMX | P51813 | 1/20 | 0.36 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
| ▸ | ITK | Q08881 | 1/20 | 0.36 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8562517 | 0.99 | KCNH2 (0.41) | KCNH2SCN5ABTKEGFRTEC | |
| SCHEMBL27366399 | 0.95 | KCNH2 (0.44) | KCNH2SCN5ABTKEGFRTEC | |
| Hydrochloric Acid SCHEMBL7504569 | 0.94 | KCNH2 (0.43) | KCNH2SCN5ABTKEGFRTEC | |
| SCHEMBL27350832 | 0.90 | KCNH2 (0.41) | KCNH2SCN5ABTKEGFRTEC | |
| Hydrochloric Acid SCHEMBL7507501 | 0.89 | KCNH2 (0.41) | KCNH2SCN5ABTKEGFRTEC | |
| SCHEMBL8566628 | 0.86 | SLC2A1 (0.47) | KCNH2SCN5ABTKSLC2A1 | |
| Hydrochloric Acid SCHEMBL8575994 | 0.85 | HRH2 (0.37) | KCNH2SCN5ABTKEGFRTEC | |
| SCHEMBL8561869 | 0.84 | DYRK3 (0.44) | KCNH2SCN5ABTK | |
| SCHEMBL8564917 | 0.84 | SCN5A (0.42) | KCNH2SCN5AKDM4EALDH1A1 | |
| SCHEMBL8561704 | 0.84 | SCN5A (0.42) | KCNH2SCN5AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0871628-A1 | QUINOLIZINONE TYPE COMPOUNDS | Abbott Laboratories (US) | 1998-10-21 | — | — | EP | claimed |
| US-5599816-A | BACTERICIDE | ABBOTT LABORATORIES (US) | 1997-02-04 | — | — | US | claimed |
| WO-1996039407-A1 | QUINOLIZINONE TYPE COMPOUNDS | ABBOTT LABORATORIES (US) | 1996-12-12 | — | — | WO | claimed |
| EP-0871628-A1 | QUINOLIZINONE TYPE COMPOUNDS | Abbott Laboratories (US) | 1998-10-21 | — | — | EP | disclosed |
| US-5726182-A | TREATMENT OF BACTERIAL INFECTIONS | ABBOTT LABORATORIES (US) | 1998-03-10 | — | — | US | disclosed |
| US-5599816-A | BACTERICIDE | ABBOTT LABORATORIES (US) | 1997-02-04 | — | — | US | disclosed |
| WO-1996039407-A1 | QUINOLIZINONE TYPE COMPOUNDS | ABBOTT LABORATORIES (US) | 1996-12-12 | — | — | WO | disclosed |