SCHEMBL8566628 — predicted protein targets

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	SLC2A1	P11166	1/20	0.47

▸	KCNH2	Q12809	8/20	0.43

▸	SCN5A	Q14524	1/20	0.40

▸	BTK	Q06187	4/20	0.35

▸	TOP1	P11387	1/20	0.34

▸	DYRK3	O43781	1/20	0.33

▸	PIM3	Q86V86	1/20	0.33

▸	SRPK1	Q96SB4	1/20	0.33

▸	CSNK1G1	Q9HCP0	1/20	0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL27366399	0.90	KCNH2 (0.44)	SLC2A1KCNH2SCN5ABTKTOP1
Hydrochloric Acid SCHEMBL7504569	0.90	KCNH2 (0.43)	SLC2A1KCNH2SCN5ABTKTOP1
SCHEMBL27350832	0.87	KCNH2 (0.41)	SLC2A1KCNH2SCN5ABTKTOP1
Hydrochloric Acid SCHEMBL7507501	0.86	KCNH2 (0.41)	SLC2A1KCNH2SCN5ABTKTOP1
SCHEMBL8561869	0.86	DYRK3 (0.44)	KCNH2SCN5ABTKTOP1DYRK3
SCHEMBL8562871	0.86	KCNH2 (0.41)	SLC2A1KCNH2SCN5ABTK
SCHEMBL8576029	0.85	KCNH2 (0.49)	SLC2A1KCNH2SCN5A
SCHEMBL8567918	0.85	KCNH2 (0.49)	SLC2A1KCNH2SCN5A
SCHEMBL8576032	0.85	KCNH2 (0.49)	SLC2A1KCNH2SCN5A
SCHEMBL14497283	0.85	SCN5A (0.43)	KCNH2SCN5ABTKTOP1DYRK3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-0871628-A1	QUINOLIZINONE TYPE COMPOUNDS	Abbott Laboratories (US)	1998-10-21	—	—	EP	disclosed