Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29467364 | 0.81 | CYP11B1 (0.36) | CYP11B1CYP11B2 | |
| SCHEMBL27347195 | 0.81 | ALDH1A1 (0.39) | LMNAALDH1A1POLBMAPTTAAR1 | |
| SCHEMBL27549672 | 0.81 | ALDH1A1 (0.43) | LMNAALDH1A1KMT2AMEN1CYP11B1 | |
| SCHEMBL5671275 | 0.81 | SIGMAR1 (0.43) | LMNAALDH1A1POLBCYP19A1 | |
| SCHEMBL28839843 | 0.81 | SIGMAR1 (0.46) | ALDH1A1MAPTKMT2AMEN1TAAR1 | |
| Hydrochloric Acid SCHEMBL27604313 | 0.80 | SIGMAR1 (0.45) | ALDH1A1MAPTKMT2AMEN1TAAR1 | |
| Hydrochloric Acid SCHEMBL28689477 | 0.79 | SIGMAR1 (0.42) | LMNAALDH1A1POLBCYP19A1L3MBTL1 | |
| Bromide SCHEMBL27702519 | 0.79 | SIGMAR1 (0.42) | LMNAALDH1A1POLBCYP19A1 | |
| SCHEMBL29761109 | 0.77 | KDM4E (0.47) | ALDH1A1POLBTAAR1GAAIDO1 | |
| SCHEMBL28109138 | 0.77 | MAPT (0.37) | LMNAALDH1A1POLBTP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1052305-A | New pyridine derivate, contain their pharmaceutical composition and preparation method thereof | RICHTER GEDEON VEGYESZET (HU) | 1991-06-19 | — | — | CN | claimed |
| CN-114736194-A | Pleuromutilin derivative containing pyridine quaternary ammonium salt side chain and having anti-pathogenic microorganism activity and preparation method and application thereof | 中牧实业股份有限公司 | 2022-07-12 | — | — | CN | disclosed |
| CN-1052305-A | New pyridine derivate, contain their pharmaceutical composition and preparation method thereof | RICHTER GEDEON VEGYESZET (HU) | 1991-06-19 | — | — | CN | disclosed |