Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 known ✓ | Q99720 | 3/20 | 0.42 |
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.38 |
| ▸ | CHRM4 known ✓ | P08173 | 1/20 | 0.38 |
| ▸ | CHRM5 known ✓ | P08912 | 1/20 | 0.38 |
| ▸ | CYP19A1 known ✓ | P11511 | 2/20 | 0.35 |
| ▸ | DRD4 known ✓ | P21917 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | PLG | P00747 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | CTSG | P08311 | 1/20 | 0.36 |
| ▸ | CMA1 | P23946 | 1/20 | 0.36 |
| ▸ | CTRC | Q99895 | 1/20 | 0.36 |
| ▸ | MC4R | P32245 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GSK3A | P49840 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5671275 | 0.98 | SIGMAR1 (0.43) | SIGMAR1CHRM2CHRM4CHRM5F2 | |
| Bromide SCHEMBL27702519 | 0.96 | SIGMAR1 (0.42) | SIGMAR1CHRM2CHRM4CHRM5F2 | |
| Pyridine SCHEMBL27810775 | 0.88 | CYP19A1 (0.38) | SIGMAR1ALDH1A1CYP19A1L3MBTL1POLB | |
| SCHEMBL28327524 | 0.83 | LTA4H (0.43) | SIGMAR1MGLL | |
| Bromide SCHEMBL28350469 | 0.83 | KCNH2 (0.39) | ALDH1A1CYP19A1KDM4ELMNA | |
| Hydrochloric Acid SCHEMBL28717343 | 0.81 | MAOA (0.45) | SIGMAR1L3MBTL1GSK3AGSK3BMGLL | |
| SCHEMBL28862078 | 0.81 | SIGMAR1 (0.50) | SIGMAR1ALDH1A1KDM4EL3MBTL1LMNA | |
| SCHEMBL30462685 | 0.81 | CYP19A1 (0.46) | ALDH1A1CYP19A1L3MBTL1LMNA | |
| Hydrochloric Acid SCHEMBL30558881 | 0.80 | ALDH1A1 (0.45) | ALDH1A1KDM4EL3MBTL1POLBTDP1 | |
| SCHEMBL29467364 | 0.79 | CYP11B1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115897065-B | Tectorial membrane composite material and preparation method and application thereof | 吴江市新三养纺织有限公司 | 2025-04-15 | — | — | CN | claimed |
| CN-115505968-A | Formula and preparation method of additive for purifying low-silver low-sulfur ultra-pure copper | 江苏鑫瑞崚新材料科技有限公司 | 2022-12-23 | — | — | CN | claimed |
| CN-114836794-A | Gold-copper alloy electroforming process and application thereof | 深圳市铭轩珠宝首饰有限公司 | 2022-08-02 | — | — | CN | claimed |
| CN-115897065-B | Tectorial membrane composite material and preparation method and application thereof | 吴江市新三养纺织有限公司 | 2025-04-15 | — | — | CN | disclosed |
| CN-119277849-A | Back contact type solar cell and preparation method thereof | 浙江福斯特新材料研究院有限公司 | 2025-01-07 | — | — | CN | disclosed |
| CN-114836794-B | Gold-copper alloy electroforming process and application thereof | 深圳市铭轩珠宝首饰有限公司 | 2024-01-30 | — | — | CN | disclosed |
| CN-114836795-B | Electroforming solution for gold cladding and preparation method and application thereof | 深圳市铭轩珠宝首饰有限公司 | 2023-12-19 | — | — | CN | disclosed |
| CN-115584253-B | Multifunctional wax-proofing agent and preparation method thereof | 中国石油天然气股份有限公司 | 2023-08-25 | — | — | CN | disclosed |
| CN-115897065-A | Film-coated composite material and preparation method and application thereof | 吴江市新三养纺织有限公司 | 2023-04-04 | — | — | CN | disclosed |
| CN-115505968-A | Formula and preparation method of additive for purifying low-silver low-sulfur ultra-pure copper | 江苏鑫瑞崚新材料科技有限公司 | 2022-12-23 | — | — | CN | disclosed |
| CN-113481551-B | Electrolyte additive of electrolytic copper foil, electrolyte, electrolytic copper foil and preparation method of electrolytic copper foil | 河南科技大学 | 2022-10-04 | — | — | CN | disclosed |
| CN-114836794-A | Gold-copper alloy electroforming process and application thereof | 深圳市铭轩珠宝首饰有限公司 | 2022-08-02 | — | — | CN | disclosed |
| CN-114836795-A | Electroforming solution for coating gold and preparation method and application thereof | 深圳市铭轩珠宝首饰有限公司 | 2022-08-02 | — | — | CN | disclosed |
| CN-107540670-B | Preparation method of 1- (3-chloropyrazolo [1,5a ] -4,5,6, 7-tetrahydropyridine-2-yl) -5-methylamine pyrazole-4-carbonitrile | 湖北相和精密化学有限公司 | 2021-08-13 | — | — | CN | disclosed |