Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 1/20 | 0.47 |
| ▸ | TOP1 | P11387 | 3/20 | 0.42 |
| ▸ | THRB | P10828 | 5/20 | 0.40 |
| ▸ | THRA | P10827 | 1/20 | 0.40 |
| ▸ | POLM | Q9NP87 | 2/20 | 0.37 |
| ▸ | POLK | Q9UBT6 | 2/20 | 0.37 |
| ▸ | POLL | Q9UGP5 | 2/20 | 0.37 |
| ▸ | POLH | Q9Y253 | 2/20 | 0.37 |
| ▸ | PTPRC | P08575 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
| ▸ | CDC25B | P30305 | 2/20 | 0.35 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | AKT1 | P31749 | 1/20 | 0.35 |
| ▸ | SNCA | P37840 | 1/20 | 0.35 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.35 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.35 |
| ▸ | NSD1 | Q96L73 | 1/20 | 0.35 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27369443 | 0.79 | PIM1 (0.46) | TOP1POLMPOLKPOLLPOLH | |
| SCHEMBL10871851 | 0.76 | THRB (0.51) | TYMSTHRBTHRAAKT1KDM4E | |
| SCHEMBL30007447 | 0.76 | THRB (0.51) | TYMSTHRBTHRAAKT1KDM4E | |
| SCHEMBL27407860 | 0.75 | POLM (0.52) | TOP1THRBPOLMPOLKPOLL | |
| SCHEMBL3841280 | 0.73 | THRB (0.56) | TYMSTHRBTHRAAKT1KDM4E | |
| SCHEMBL29413361 | 0.73 | THRB (0.56) | TYMSTHRBTHRAAKT1KDM4E | |
| SCHEMBL27370235 | 0.73 | POLM (0.60) | TOP1POLMPOLKPOLLPOLH | |
| SCHEMBL28729483 | 0.72 | TYMS (0.47) | TYMSTOP1THRBTHRAAKT1 | |
| SCHEMBL28406639 | 0.72 | TYMS (0.47) | TYMSTOP1THRBTHRAAKT1 | |
| SCHEMBL1508109 | 0.72 | TYMS (0.56) | TYMSTHRBTHRAKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1063180-C | 5H, 10H-imidazo [1, 2 -a] indeno [1, 2 -e] pyrazin-4-one derivatives, preparation thereof, and drugs containing said derivatives | RHONE POULENC RORER SA (FR) | 2001-03-14 | — | — | CN | disclosed |
| CN-1180357-A | 5H, 10H-imidazo [1, 2-a ] indeno [1, 2-e ] pyrazin-4-one derivatives, preparation thereof and medicaments containing same | RHONE POULENC RORER SA (FR) | 1998-04-29 | — | — | CN | disclosed |