Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14174940 | 0.82 | KDM4E (0.36) | KDM4EALDH1A1TDP1HRH3 | |
| SCHEMBL14174929 | 0.77 | KDM4E (0.37) | KDM4EALDH1A1TDP1HRH3 | |
| SCHEMBL12536208 | 0.74 | HRH3 (0.42) | HRH3 | |
| SCHEMBL25818430 | 0.74 | HRH3 (0.41) | KDM4EALDH1A1TDP1HRH3 | |
| SCHEMBL23806161 | 0.73 | SIGMAR1 (0.35) | KDM4EALDH1A1TDP1HRH3 | |
| SCHEMBL4544646 | 0.73 | NCF1 (0.50) | HRH3 | |
| SCHEMBL14593629 | 0.71 | HTT (0.30) | — | |
| SCHEMBL9130127 | 0.71 | — | — | |
| SCHEMBL13967030 | 0.71 | GNAO1 (0.47) | HRH3 | |
| SCHEMBL8285967 | 0.70 | PHGDH (0.37) | KDM4EALDH1A1TDP1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024057021-A1 | COMPOUNDS FOR TARGETED PROTEIN DEGRADATION | AMPHISTA THERAPEUTICS LIMITED (GB) | 2024-03-21 | — | — | WO | disclosed |